Term Information

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Accession
GO:0003935
Name
GTP cyclohydrolase II activity
Ontology
molecular_function
Synonyms
GTP 7,8-8,9-dihydrolase (diphosphate-forming), GTP-8-formylhydrolase activity, guanosine triphosphate cyclohydrolase II
Alternate IDs
None
Definition
Catalysis of the reaction: GTP + 4 H2O = 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)-pyrimidine + formate + 3 H+ + 2 phosphate. Source: EC:3.5.4.25, RHEA:23704
Comment
None
History
See term history for GO:0003935 at QuickGO
Chem. react.
has participant GTP(4-)
has participant hydrogenphosphate
has participant formate
has participant 2,5-diamino-4-hydroxy-6-(5-phosphonatoribosylamino)pyrimidine(3-)
has participant water
has participant hydron
Subset
None
Include "regulates"
For more information, please see the ontology relation documentation.

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Parents of GTP cyclohydrolase II activity (GO:0003935)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
GTP cyclohydrolase II activity [RO:0000057 relation] RO:0000057  GTP(4-) (CHEBI:37565)
GTP cyclohydrolase II activity [RO:0000057 relation] RO:0000057  hydrogenphosphate (CHEBI:43474)
GTP cyclohydrolase II activity [RO:0000057 relation] RO:0000057  formate (CHEBI:15740)
GTP cyclohydrolase II activity [RO:0000057 relation] RO:0000057  2,5-diamino-4-hydroxy-6-(5-phosphonatoribosylamino)pyrimidine(3-) (CHEBI:58614)
GTP cyclohydrolase II activity [RO:0000057 relation] RO:0000057  water (CHEBI:15377)
GTP cyclohydrolase II activity [is_a relation] is_a  GTP cyclohydrolase activity (GO:0003933)
GTP cyclohydrolase II activity [RO:0000057 relation] RO:0000057  hydron (CHEBI:15378)

This term has no children.

EC
3.5.4.25
KEGG_REACTION
R00425
MetaCyc
GTP-CYCLOHYDRO-II-RXN
RHEA
23704