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L-iditol 2-dehydrogenase activity

Term Information

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Accession
GO:0003939
Name
L-iditol 2-dehydrogenase activity
Ontology
molecular_function
Synonyms
L-iditol (sorbitol) dehydrogenase activity, L-iditol:NAD oxidoreductase activity, L-iditol:NAD+ 5-oxidoreductase activity, NAD+-dependent sorbitol dehydrogenase activity, NAD-dependent sorbitol dehydrogenase activity, NAD-sorbitol dehydrogenase, glucitol dehydrogenase activity, sorbitol dehydrogenase activity, polyol dehydrogenase activity
Alternate IDs
None
Definition
Catalysis of the reaction: L-iditol + NAD+ = L-sorbose + NADH + H+. Source: EC:1.1.1.14
Comment
Note that enzymes with this activity also act on D-glucitol (giving D-fructose) and other closely related sugar alcohols.
History
See term history for GO:0003939 at QuickGO
Chem. react.
has participant L-iditol
has participant NAD(1-)
has participant keto-L-sorbose
has participant NADH(2-)
has participant hydron
Subset
None
Include "regulates"
For more information, please see the ontology relation documentation.

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Graph of GO:0003939 from QuickGO

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Parents of L-iditol 2-dehydrogenase activity (GO:0003939)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
L-iditol 2-dehydrogenase activity [RO:0000057 relation] RO:0000057  L-iditol (CHEBI:18202)
L-iditol 2-dehydrogenase activity [is_a relation] is_a  oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (GO:0016616)
L-iditol 2-dehydrogenase activity [RO:0000057 relation] RO:0000057  NAD(1-) (CHEBI:57540)
L-iditol 2-dehydrogenase activity [RO:0000057 relation] RO:0000057  keto-L-sorbose (CHEBI:13172)
L-iditol 2-dehydrogenase activity [RO:0000057 relation] RO:0000057  NADH(2-) (CHEBI:57945)
L-iditol 2-dehydrogenase activity [RO:0000057 relation] RO:0000057  hydron (CHEBI:15378)

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