AmiGO 2: Term Details for "NADPH-hemoprotein reductase activity" (GO:0003958)

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Term Information

Accession: GO:0003958
Name: NADPH-hemoprotein reductase activity
Ontology: molecular_function
Synonyms: NADPH-ferrihemoprotein reductase activity, NADPH:cytochrome P450 reductase activity, NADPH:cytochrome c reductase activity, CPR activity, FAD-cytochrome c reductase activity, NADPH-cytochrome P-450 oxidoreductase activity, NADPH-cytochrome p-450 reductase activity, NADPH:P-450 reductase activity, NADPH:ferrihemoprotein oxidoreductase activity, NADPH:hemoprotein oxidoreductase activity, POR, TPNH2 cytochrome c reductase activity, aldehyde reductase (NADPH-dependent) activity, cytochrome P-450 reductase activity, ferrihemoprotein P-450 reductase activity, NADP--cytochrome c reductase activity, NADP--cytochrome reductase activity, NADPH--cytochrome P450 oxidoreductase activity, NADPH--cytochrome P450 reductase activity, NADPH--cytochrome c oxidoreductase activity, NADPH--cytochrome c reductase activity, NADPH--ferricytochrome c oxidoreductase activity, NADPH--ferrihemoprotein reductase activity, NADPH-dependent cytochrome c reductase activity, NADPH:P450 reductase activity, TPNH(2) cytochrome c reductase activity, TPNH-cytochrome c reductase activity, cytochrome P450 reductase activity, cytochrome c reductase (reduced nicotinamide adenine dinucleotide phosphate, NADPH, NADPH-dependent) activity, dihydroxynicotinamide adenine dinucleotide phosphate-cytochrome c reductase activity, reduced nicotinamide adenine dinucleotide phosphate-cytochrome c reductase activity, reductase, cytochrome c (reduced nicotinamide adenine dinucleotide phosphate) activity
Alternate IDs: None
Definition: Catalysis of the reaction: NADPH + H+ + n oxidized hemoprotein = NADP+ + n reduced hemoprotein. Source: EC:1.6.2.4
Comment: None
History: See term history for GO:0003958 at QuickGO
Chem. react.: has participant ferriheme b(1-); has participant ferroheme b(2-); has participant NADPH(4-); has participant NADP(3-); has participant hydron
Subset: None
Related: Link to all genes and gene products annotated to NADPH-hemoprotein reductase activity (excluding "regulates").; Link to all direct and indirect annotations to NADPH-hemoprotein reductase activity (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for NADPH-hemoprotein reductase activity (excluding "regulates").

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Additional internal viewing options

GO:0003674 molecular_function
GO:0003824 catalytic activity
GO:0016491 oxidoreductase activity
GO:0016651 oxidoreductase activity, acting on NAD(P)H
GO:0016653 oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor
GO:0003958 NADPH-hemoprotein reductase activity

Parents of NADPH-hemoprotein reductase activity (GO:0003958)

subject	relation	object
NADPH-hemoprotein reductase activity	is_a	oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor (GO:0016653)
NADPH-hemoprotein reductase activity	RO:0000057	ferriheme b(1-) (CHEBI:55376)
NADPH-hemoprotein reductase activity	RO:0000057	ferroheme b(2-) (CHEBI:60344)
NADPH-hemoprotein reductase activity	RO:0000057	NADPH(4-) (CHEBI:57783)
NADPH-hemoprotein reductase activity	RO:0000057	NADP(3-) (CHEBI:58349)
NADPH-hemoprotein reductase activity	RO:0000057	hydron (CHEBI:15378)

This term has no children.

EC: 1.6.2.4
MetaCyc: NADPH--FERRIHEMOPROTEIN-REDUCTASE-RXN
Reactome: R-HSA-76494
RHEA: 24040