AmiGO 2: Term Details for "acetate-CoA ligase activity" (GO:0003987)

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Term Information

Accession: GO:0003987
Name: acetate-CoA ligase activity
Ontology: molecular_function
Synonyms: ACS, acetate to acetyl-CoA, acetate:CoA ligase (AMP-forming), acetic thiokinase activity, acetyl CoA ligase activity, acetyl CoA synthase activity, acetyl activating enzyme, acetyl coenzyme A synthetase activity, acetyl-CoA synthase activity, acetyl-CoA synthetase activity, acetyl-activating enzyme activity, acetyl-coenzyme A synthase activity, short chain fatty acyl-CoA synthetase activity, short-chain acyl-coenzyme A synthetase activity, acetate thiokinase activity, acyl-activating enzyme activity
Alternate IDs: None
Definition: Catalysis of the reaction: ATP + acetate + CoA = AMP + diphosphate + acetyl-CoA. Source: EC:6.2.1.1
Comment: None
History: See term history for GO:0003987 at QuickGO
Chem. react.: has participant coenzyme A(4-); has participant adenosine 5'-monophosphate(2-); has participant acetate; has participant acetyl-CoA(4-); has participant ATP(4-); has participant diphosphate(3-)
Subset: None
Related: Link to all genes and gene products annotated to acetate-CoA ligase activity (excluding "regulates").; Link to all direct and indirect annotations to acetate-CoA ligase activity (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for acetate-CoA ligase activity (excluding "regulates").

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GO:0003674 molecular_function
GO:0003824 catalytic activity
GO:0016874 ligase activity
GO:0016877 ligase activity, forming carbon-sulfur bonds
GO:0016878 acid-thiol ligase activity
GO:0016405 CoA-ligase activity
GO:0003987 acetate-CoA ligase activity

Parents of acetate-CoA ligase activity (GO:0003987)

subject	relation	object
acetate-CoA ligase activity	RO:0000057	coenzyme A(4-) (CHEBI:57287)
acetate-CoA ligase activity	is_a	acid-thiol ligase activity (GO:0016878)
acetate-CoA ligase activity	RO:0000057	adenosine 5'-monophosphate(2-) (CHEBI:456215)
acetate-CoA ligase activity	RO:0000057	acetate (CHEBI:30089)
acetate-CoA ligase activity	RO:0000057	acetyl-CoA(4-) (CHEBI:57288)
acetate-CoA ligase activity	is_a	CoA-ligase activity (GO:0016405)
acetate-CoA ligase activity	RO:0000057	ATP(4-) (CHEBI:30616)
acetate-CoA ligase activity	RO:0000057	diphosphate(3-) (CHEBI:33019)

This term has no children.

EC: 6.2.1.1
MetaCyc: ACETATE--COA-LIGASE-RXN
Reactome: R-HSA-71735; R-HSA-449911; R-HSA-8875071
RHEA: 23176