Term Information

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Accession
GO:0004032
Name
aldose reductase (NADPH) activity
Ontology
molecular_function
Synonyms
alditol:NADP+ 1-oxidoreductase activity, aldehyde reductase activity, aldose reductase activity, polyol dehydrogenase (NADP(+)) activity
Alternate IDs
None
Definition
Catalysis of the reaction: an alditol + NADP+ = an aldose + NADPH + H+. Source: EC:1.1.1.21
Comment
None
History
See term history for GO:0004032 at QuickGO
Chem. react.
has participant aldose
has participant NADP(3-)
has participant NADPH(4-)
has participant alditol
has participant hydron
Subset
None
Include "regulates"
For more information, please see the ontology relation documentation.

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Graph of GO:0004032 from QuickGO

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Parents of aldose reductase (NADPH) activity (GO:0004032)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
aldose reductase (NADPH) activity [RO:0000057 relation] RO:0000057  aldose (CHEBI:15693)
aldose reductase (NADPH) activity [RO:0000057 relation] RO:0000057  NADP(3-) (CHEBI:58349)
aldose reductase (NADPH) activity [RO:0000057 relation] RO:0000057  NADPH(4-) (CHEBI:57783)
aldose reductase (NADPH) activity [RO:0000057 relation] RO:0000057  alditol (CHEBI:17522)
aldose reductase (NADPH) activity [RO:0000057 relation] RO:0000057  hydron (CHEBI:15378)
aldose reductase (NADPH) activity [is_a relation] is_a  alcohol dehydrogenase (NADP+) activity (GO:0008106)
Children of aldose reductase (NADPH) activity (GO:0004032)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
L-arabinose reductase (NADPH) activity (GO:0032867) [is_a relation] is_a  aldose reductase (NADPH) activity
D-xylose reductase (NADPH) activity (GO:0032866) [is_a relation] is_a  aldose reductase (NADPH) activity
EC
1.1.1.21
KEGG_REACTION
R02820
MetaCyc
ALDEHYDE-REDUCTASE-RXN
Reactome
R-HSA-5652172
R-HSA-196060
RHEA
12789