AmiGO 2: Term Details for "amidase activity" (GO:0004040)

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Term Information

Accession: GO:0004040
Name: amidase activity
Ontology: molecular_function
Synonyms: acetamidase activity, N-acetylaminohydrolase activity, acylamidase activity, acylamide amidohydrolase activity, acylase activity, amidohydrolase activity, fatty acylamidase activity
Alternate IDs: None
Definition: Catalysis of the reaction: a monocarboxylic acid amide + H2O = a monocarboxylate + NH3. Source: EC:3.5.1.4
Comment: None
History: See term history for GO:0004040 at QuickGO
Chem. react.: has participant monocarboxylic acid anion; has participant N-acylammonia; has participant water; has participant ammonium
Subset: None
Related: Link to all genes and gene products annotated to amidase activity (excluding "regulates").; Link to all direct and indirect annotations to amidase activity (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for amidase activity (excluding "regulates").

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For more information, please see the ontology relation documentation.

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GO:0003674 molecular_function
GO:0003824 catalytic activity
GO:0016787 hydrolase activity
GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
GO:0004040 amidase activity

Parents of amidase activity (GO:0004040)

subject	relation	object
amidase activity	RO:0000057	monocarboxylic acid anion (CHEBI:35757)
amidase activity	RO:0000057	N-acylammonia (CHEBI:83628)
amidase activity	RO:0000057	water (CHEBI:15377)
amidase activity	RO:0000057	ammonium (CHEBI:28938)
amidase activity	is_a	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides (GO:0016811)

This term has no children.

EC: 3.5.1.4
MetaCyc: AMIDASE-RXN
RHEA: 12020
UM-BBD_enzymeID: e0068