AmiGO 2: Term Details for "apyrase activity" (GO:0004050)

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Term Information

Accession: GO:0004050
Name: apyrase activity
Ontology: molecular_function
Synonyms: None
Alternate IDs: None
Definition: Catalysis of the reaction: a ribonucleoside 5'-triphosphate + 2 H2O = a ribonucleoside 5'-phosphate + 2 phosphate. This reaction consists of two distinct successive phosphate-releasing steps, with NDPs as intermediates. Apyrases are active against both di- and triphosphate nucleotides (NDPs and NTPs) and hydrolyze NTPs to nucleotide monophosphates (NMPs). Source: EC:3.6.1.5
Comment: None
History: See term history for GO:0004050 at QuickGO
Chem. react.: has participant hydron; has participant nucleoside 5'-monophosphate(2-); has participant nucleoside 5'-triphoshate(4-); has participant hydrogenphosphate; has participant water
Subset: None
Related: Link to all genes and gene products annotated to apyrase activity (excluding "regulates").; Link to all direct and indirect annotations to apyrase activity (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for apyrase activity (excluding "regulates").

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For more information, please see the ontology relation documentation.

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Additional internal viewing options

GO:0003674 molecular_function
GO:0003824 catalytic activity
GO:0016787 hydrolase activity
GO:0016817 hydrolase activity, acting on acid anhydrides
GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
GO:0016462 pyrophosphatase activity
GO:0004050 apyrase activity

Parents of apyrase activity (GO:0004050)

subject	relation	object
apyrase activity	RO:0000057	hydron (CHEBI:15378)
apyrase activity	RO:0000057	nucleoside 5'-monophosphate(2-) (CHEBI:58043)
apyrase activity	is_a	pyrophosphatase activity (GO:0016462)
apyrase activity	RO:0000057	nucleoside 5'-triphoshate(4-) (CHEBI:61557)
apyrase activity	RO:0000057	hydrogenphosphate (CHEBI:43474)
apyrase activity	RO:0000057	water (CHEBI:15377)

This term has no children.

EC: 3.6.1.5
MetaCyc: APYRASE-RXN
RHEA: 36795