AmiGO 2: Term Details for "arginase activity" (GO:0004053)

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Term Information

Accession: GO:0004053
Name: arginase activity
Ontology: molecular_function
Synonyms: L-arginase activity, L-arginine amidinohydrolase activity, arginine amidinase activity, arginine transamidinase activity, canavanase activity
Alternate IDs: None
Definition: Catalysis of the reaction: L-arginine + H2O = L-ornithine + urea. Source: EC:3.5.3.1
Comment: None
History: See term history for GO:0004053 at QuickGO
Chem. react.: has participant L-argininium(1+); has participant urea; has participant L-ornithinium(1+); has participant water
Subset: None
Related: Link to all genes and gene products annotated to arginase activity (excluding "regulates").; Link to all direct and indirect annotations to arginase activity (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for arginase activity (excluding "regulates").

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For more information, please see the ontology relation documentation.

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Additional internal viewing options

GO:0003674 molecular_function
GO:0003824 catalytic activity
GO:0016787 hydrolase activity
GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
GO:0004053 arginase activity
GO:0150071 negative regulation of arginase activity
GO:0150072 positive regulation of arginase activity
GO:0150070 regulation of arginase activity

Parents of arginase activity (GO:0004053)

subject	relation	object
arginase activity	RO:0000057	L-argininium(1+) (CHEBI:32682)
arginase activity	is_a	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines (GO:0016813)
arginase activity	RO:0000057	urea (CHEBI:16199)
arginase activity	RO:0000057	L-ornithinium(1+) (CHEBI:46911)
arginase activity	RO:0000057	water (CHEBI:15377)

Children of arginase activity (GO:0004053)

subject	relation	object
regulation of arginase activity (GO:0150070)	RO:0002211	arginase activity
positive regulation of arginase activity (GO:0150072)	RO:0002213	arginase activity
negative regulation of arginase activity (GO:0150071)	RO:0002212	arginase activity

EC: 3.5.3.1
MetaCyc: ARGINASE-RXN
Reactome: R-HSA-70569; R-HSA-452036
RHEA: 20569