Term Information

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Accession
GO:0004076
Name
biotin synthase activity
Ontology
molecular_function
Synonyms
biotin synthetase activity, dethiobiotin:sulfur sulfurtransferase activity
Alternate IDs
None
Definition
Catalysis of the reaction: 2 S-adenosyl-L-methionine + dethiobiotin + S(2-) = 2 5'-deoxyadenosine + 2 L-methionine + biotin + H+. Source: EC:2.8.1.6, RHEA:22060
Comment
None
History
See term history for GO:0004076 at QuickGO
Chem. react.
has participant S-adenosyl-L-methionine zwitterion
has participant di-mu-sulfido-diiron(1+)
has participant H group
has participant biotinate
has participant thiol group
has participant 5'-deoxyadenosine
has participant di-mu-sulfido-diiron(2+)
has participant L-methionine zwitterion
has participant (4R,5S)-dethiobiotin(1-)
Subset
None
Include "regulates"
For more information, please see the ontology relation documentation.

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Graph of GO:0004076 from QuickGO

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Parents of biotin synthase activity (GO:0004076)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
biotin synthase activity [RO:0000057 relation] RO:0000057  S-adenosyl-L-methionine zwitterion (CHEBI:59789)
biotin synthase activity [RO:0000057 relation] RO:0000057  di-mu-sulfido-diiron(1+) (CHEBI:33738)
biotin synthase activity [RO:0000057 relation] RO:0000057  H group (CHEBI:64428)
biotin synthase activity [RO:0000057 relation] RO:0000057  biotinate (CHEBI:57586)
biotin synthase activity [RO:0000057 relation] RO:0000057  thiol group (CHEBI:29917)
biotin synthase activity [RO:0000057 relation] RO:0000057  5'-deoxyadenosine (CHEBI:17319)
biotin synthase activity [RO:0000057 relation] RO:0000057  di-mu-sulfido-diiron(2+) (CHEBI:33737)
biotin synthase activity [RO:0000057 relation] RO:0000057  L-methionine zwitterion (CHEBI:57844)
biotin synthase activity [is_a relation] is_a  sulfurtransferase activity (GO:0016783)
biotin synthase activity [RO:0000057 relation] RO:0000057  (4R,5S)-dethiobiotin(1-) (CHEBI:149473)

This term has no children.

EC
2.8.1.6
KEGG_REACTION
R01078
MetaCyc
2.8.1.6-RXN
RHEA
22060