AmiGO 2: Term Details for "citrate (Si)-synthase activity" (GO:0004108)

Term Information

Accession: GO:0004108
Name: citrate (Si)-synthase activity
Ontology: molecular_function
Synonyms: (R)-citric synthase activity, acetyl-CoA:oxaloacetate C-acetyltransferase [thioester-hydrolysing, (pro-S)-carboxymethyl forming], citrate condensing enzyme activity, citrate oxaloacetate-lyase ((pro-3S)-CH(2)COO(-)->acetyl-CoA) activity, citrate oxaloacetate-lyase ((pro-3S)-CH2COO-rightacetyl-CoA), citrate oxaloacetate-lyase [(pro-3S)-CH2COOrightacetyl-CoA], citrate oxaloacetate-lyase, CoA-acetylating activity, citrate synthetase activity, citric synthase activity, citric-condensing enzyme activity, citrogenase activity, oxalacetic transacetase activity, oxaloacetate transacetase activity, citrate synthase activity, condensing enzyme activity
Alternate IDs: None
Definition: Catalysis of the reaction: acetyl-CoA + H2O + oxaloacetate = citrate + CoA, where the acetyl group is added to the si-face of oxaloacetate; acetyl-CoA thus provides the two carbon atoms of the pro-S carboxymethyl group. Source: EC:2.3.3.1
Comment: Note that this function was formerly EC:4.1.3.7.
History: See term history for GO:0004108 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to citrate (Si)-synthase activity (excluding "regulates").; Link to all direct and indirect annotations to citrate (Si)-synthase activity (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for citrate (Si)-synthase activity (excluding "regulates").

Include "regulates"
For more information, please see the ontology relation documentation.

Filter results

View this term in QuickGO.

Additional external viewing options

OLSVis (interactive)

Additional internal viewing options

GO:0003674 molecular_function
GO:0003824 catalytic activity
GO:0016740 transferase activity
GO:0016746 acyltransferase activity
GO:0046912 acyltransferase activity, acyl groups converted into alkyl on transfer
GO:0036440 citrate synthase activity
GO:0004108 citrate (Si)-synthase activity

Parents of citrate (Si)-synthase activity (GO:0004108)

subject	relation	object
citrate (Si)-synthase activity	is_a	citrate synthase activity (GO:0036440)

This term has no children.

EC: 2.3.3.1
MetaCyc: CITSYN-RXN
Reactome: R-HSA-70975