Term Information

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Accession
GO:0004114
Name
3',5'-cyclic-nucleotide phosphodiesterase activity
Ontology
molecular_function
Synonyms
3',5' cyclic-nucleotide phosphodiesterase activity, 3', 5'-cyclic nucleoside monophosphate phosphodiesterase activity, 3',5'-cyclic-nucleotide 5'-nucleotidohydrolase activity, 3',5'-cyclonucleotide phosphodiesterase activity, 3',5'-nucleotide phosphodiesterase activity, 3': 5'-monophosphate phosphodiesterase (cyclic CMP) activity, 3':5'-cyclic nucleotide 5'-nucleotidohydrolase activity, PDE, cyclic 3',5'-mononucleotide phosphodiesterase activity, cyclic 3',5'-nucleotide phosphodiesterase activity, cyclic 3',5'-phosphodiesterase activity, cyclic 3',5-nucleotide monophosphate phosphodiesterase activity, cyclic nucleotide phosphodiesterase activity, cytidine 3':5'-monophosphate phosphodiesterase (cyclic CMP) activity, nucleoside 3',5'-cyclic phosphate diesterase activity, nucleoside-3',5-monophosphate phosphodiesterase activity, cyclic AMP phosphodiesterase activity
Alternate IDs
None
Definition
Catalysis of the reaction: a nucleoside 3',5'-cyclic phosphate + H2O = a nucleoside 5'-phosphate. Source: RHEA:14653
Comment
None
History
See term history for GO:0004114 at QuickGO
Chem. react.
has participant nucleoside 3',5'-cyclic phosphate anion
has participant water
has participant hydron
has participant nucleoside 5'-phosphate dianion
Subset
None
Include "regulates"
For more information, please see the ontology relation documentation.

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Graph of GO:0004114 from QuickGO

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Parents of 3',5'-cyclic-nucleotide phosphodiesterase activity (GO:0004114)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
3',5'-cyclic-nucleotide phosphodiesterase activity [is_a relation] is_a  cyclic-nucleotide phosphodiesterase activity (GO:0004112)
3',5'-cyclic-nucleotide phosphodiesterase activity [RO:0000057 relation] RO:0000057  nucleoside 3',5'-cyclic phosphate anion (CHEBI:58464)
3',5'-cyclic-nucleotide phosphodiesterase activity [RO:0000057 relation] RO:0000057  water (CHEBI:15377)
3',5'-cyclic-nucleotide phosphodiesterase activity [RO:0000057 relation] RO:0000057  hydron (CHEBI:15378)
3',5'-cyclic-nucleotide phosphodiesterase activity [RO:0000057 relation] RO:0000057  nucleoside 5'-phosphate dianion (CHEBI:57867)
Children of 3',5'-cyclic-nucleotide phosphodiesterase activity (GO:0004114)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
3',5'-cyclic-AMP phosphodiesterase activity (GO:0004115) [is_a relation] is_a  3',5'-cyclic-nucleotide phosphodiesterase activity
photoreceptor cyclic-nucleotide phosphodiesterase activity (GO:0004120) [is_a relation] is_a  3',5'-cyclic-nucleotide phosphodiesterase activity
3',5'-cyclic-GMP phosphodiesterase activity (GO:0047555) [is_a relation] is_a  3',5'-cyclic-nucleotide phosphodiesterase activity
cGMP-stimulated cyclic-nucleotide phosphodiesterase activity (GO:0004118) [is_a relation] is_a  3',5'-cyclic-nucleotide phosphodiesterase activity
cGMP-inhibited cyclic-nucleotide phosphodiesterase activity (GO:0004119) [is_a relation] is_a  3',5'-cyclic-nucleotide phosphodiesterase activity
EC
3.1.4.17
MetaCyc
3.1.4.17-RXN
Reactome
R-HSA-162425
RHEA
14653