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dihydrolipoyl dehydrogenase activity

Term Information

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Accession
GO:0004148
Name
dihydrolipoyl dehydrogenase activity
Ontology
molecular_function
Synonyms
E3 component of alpha-ketoacid dehydrogenase complexes activity, L-protein activity, dehydrolipoate dehydrogenase activity, diaphorase activity, dihydrolipoamide dehydrogenase activity, dihydrolipoamide reduction, dihydrolipoamide:NAD+ oxidoreductase, dihydrolipoic dehydrogenase activity, dihydrolipoylprotein reduction, dihydrothioctic dehydrogenase activity, glycine-cleavage system L-protein activity, lipoamide dehydrogenase (NADH) activity, lipoamide oxidoreductase (NADH) activity, lipoamide reductase (NADH) activity, lipoamide reductase activity, lipoate dehydrogenase activity, lipoic acid dehydrogenase activity, lipoyl dehydrogenase activity, protein-6-N-(dihydrolipoyl)lysine:NAD+ oxidoreductase, protein-N6-(dihydrolipoyl)lysine:NAD+ oxidoreductase, LDP-Glc activity, LDP-Val activity
Alternate IDs
None
Definition
Catalysis of the reaction: protein N6-(dihydrolipoyl)lysine + NAD+ = protein N6-(lipoyl)lysine + NADH + H+. Source: EC:1.8.1.4
Comment
None
History
See term history for GO:0004148 at QuickGO
Chem. react.
has participant N(6)-[(R)-dihydrolipoyl]-L-lysine residue
has participant N(6)-[(R)-lipoyl]-L-lysine residue
has participant hydron
has participant NADH(2-)
has participant NAD(1-)
Subset
None
Include "regulates"
For more information, please see the ontology relation documentation.

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Graph of GO:0004148 from QuickGO

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Parents of dihydrolipoyl dehydrogenase activity (GO:0004148)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
dihydrolipoyl dehydrogenase activity [RO:0000057 relation] RO:0000057  N(6)-[(R)-dihydrolipoyl]-L-lysine residue (CHEBI:83100)
dihydrolipoyl dehydrogenase activity [is_a relation] is_a  oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor (GO:0016668)
dihydrolipoyl dehydrogenase activity [RO:0000057 relation] RO:0000057  N(6)-[(R)-lipoyl]-L-lysine residue (CHEBI:83099)
dihydrolipoyl dehydrogenase activity [RO:0000057 relation] RO:0000057  hydron (CHEBI:15378)
dihydrolipoyl dehydrogenase activity [RO:0000057 relation] RO:0000057  NADH(2-) (CHEBI:57945)
dihydrolipoyl dehydrogenase activity [RO:0000057 relation] RO:0000057  NAD(1-) (CHEBI:57540)

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