AmiGO 2: Term Details for "dihydroorotase activity" (GO:0004151)

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Term Information

Accession: GO:0004151
Name: dihydroorotase activity
Ontology: molecular_function
Synonyms: (S)-dihydroorotate amidohydrolase activity, DHOase activity, carbamoylaspartic dehydrase activity, dihydroorotate hydrolase activity
Alternate IDs: None
Definition: Catalysis of the reaction: (S)-dihydroorotate + H2O = N-carbamoyl-L-aspartate + H+. Source: RHEA:24296, EC:3.5.2.3
Comment: None
History: See term history for GO:0004151 at QuickGO
Chem. react.: has participant (S)-dihydroorotate; has participant water; has participant hydron; has participant N-carbamoyl-L-aspartate(2-)
Subset: None
Related: Link to all genes and gene products annotated to dihydroorotase activity (excluding "regulates").; Link to all direct and indirect annotations to dihydroorotase activity (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for dihydroorotase activity (excluding "regulates").

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For more information, please see the ontology relation documentation.

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Additional internal viewing options

GO:0003674 molecular_function
GO:0003824 catalytic activity
GO:0016787 hydrolase activity
GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GO:0004151 dihydroorotase activity

Parents of dihydroorotase activity (GO:0004151)

subject	relation	object
dihydroorotase activity	RO:0000057	(S)-dihydroorotate (CHEBI:30864)
dihydroorotase activity	is_a	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides (GO:0016812)
dihydroorotase activity	RO:0000057	water (CHEBI:15377)
dihydroorotase activity	RO:0000057	hydron (CHEBI:15378)
dihydroorotase activity	RO:0000057	N-carbamoyl-L-aspartate(2-) (CHEBI:32814)

This term has no children.

EC: 3.5.2.3
KEGG_REACTION: R01993
MetaCyc: DIHYDROOROT-RXN
Reactome: R-HSA-73571
RHEA: 24296