AmiGO 2: Term Details for "aminopeptidase activity" (GO:0004177)

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Term Information

Accession: GO:0004177
Name: aminopeptidase activity
Ontology: molecular_function
Synonyms: None
Alternate IDs: None
Definition: Catalysis of the hydrolysis of a single N-terminal amino acid residue from a polypeptide chain. Source: PMID:24157837, https://www.ebi.ac.uk/merops/about/glossary.shtml#AMINOPEPTIDASE
Comment: None
History: See term history for GO:0004177 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to aminopeptidase activity (excluding "regulates").; Link to all direct and indirect annotations to aminopeptidase activity (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for aminopeptidase activity (excluding "regulates").

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For more information, please see the ontology relation documentation.

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GO:0003674 molecular_function
GO:0003824 catalytic activity
GO:0140096 catalytic activity, acting on a protein
GO:0016787 hydrolase activity
GO:0008233 peptidase activity
GO:0008238 exopeptidase activity
GO:0004177 aminopeptidase activity
GO:0070005 cysteine-type aminopeptidase activity
GO:0004239 initiator methionyl aminopeptidase activity
GO:0070006 metalloaminopeptidase activity
GO:0070009 serine-type aminopeptidase activity
GO:0045148 tripeptide aminopeptidase activity

Parents of aminopeptidase activity (GO:0004177)

subject	relation	object
aminopeptidase activity	is_a	exopeptidase activity (GO:0008238)

Children of aminopeptidase activity (GO:0004177)

subject	relation	object
tripeptide aminopeptidase activity (GO:0045148)	is_a	aminopeptidase activity
metalloaminopeptidase activity (GO:0070006)	is_a	aminopeptidase activity
cysteine-type aminopeptidase activity (GO:0070005)	is_a	aminopeptidase activity
serine-type aminopeptidase activity (GO:0070009)	is_a	aminopeptidase activity
initiator methionyl aminopeptidase activity (GO:0004239)	is_a	aminopeptidase activity

EC: 3.4.11.21; 3.4.11.9; 3.4.11.6; 3.4.11.5; 3.4.11.-
MetaCyc: 3.4.11.21-RXN; RXN0-5052; 3.4.11.6-RXN; 3.4.11.9-RXN; 3.4.11.5-RXN
Reactome: R-HSA-983162; R-HSA-1236954; R-HSA-2534096