AmiGO 2: Term Details for "epoxide hydrolase activity" (GO:0004301)

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Term Information

Accession: GO:0004301
Name: epoxide hydrolase activity
Ontology: molecular_function
Synonyms: cytosolic epoxide hydrolase activity, sEH, trans-stilbene oxide hydrolase activity, soluble epoxide hydrolase activity, arene-oxide hydratase activity, aryl epoxide hydrase activity, epoxide hydrase activity, epoxide hydratase activity
Alternate IDs: None
Definition: Catalysis of the reaction: an epoxide + H2O = an ethanediol. Source: EC:3.3.2.10
Comment: None
History: See term history for GO:0004301 at QuickGO
Chem. react.: has participant ethanediol derivative; has participant water; has participant epoxide
Subset: goslim_chembl
Related: Link to all genes and gene products annotated to epoxide hydrolase activity (excluding "regulates").; Link to all direct and indirect annotations to epoxide hydrolase activity (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for epoxide hydrolase activity (excluding "regulates").

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For more information, please see the ontology relation documentation.

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GO:0003674 molecular_function
GO:0003824 catalytic activity
GO:0016787 hydrolase activity
GO:0016801 hydrolase activity, acting on ether bonds
GO:0016803 ether hydrolase activity
GO:0004301 epoxide hydrolase activity
GO:0033961 cis-stilbene-oxide hydrolase activity
GO:0047977 hepoxilin-epoxide hydrolase activity
GO:0008096 juvenile hormone epoxide hydrolase activity
GO:0018744 limonene-1,2-epoxide hydrolase activity
GO:0019118 phenanthrene-epoxide hydrolase activity

Parents of epoxide hydrolase activity (GO:0004301)

subject	relation	object
epoxide hydrolase activity	RO:0000057	ethanediol derivative (CHEBI:140594)
epoxide hydrolase activity	RO:0000057	water (CHEBI:15377)
epoxide hydrolase activity	is_a	ether hydrolase activity (GO:0016803)
epoxide hydrolase activity	RO:0000057	epoxide (CHEBI:32955)

Children of epoxide hydrolase activity (GO:0004301)

subject	relation	object
limonene-1,2-epoxide hydrolase activity (GO:0018744)	is_a	epoxide hydrolase activity
cis-stilbene-oxide hydrolase activity (GO:0033961)	is_a	epoxide hydrolase activity
hepoxilin-epoxide hydrolase activity (GO:0047977)	is_a	epoxide hydrolase activity
phenanthrene-epoxide hydrolase activity (GO:0019118)	is_a	epoxide hydrolase activity
juvenile hormone epoxide hydrolase activity (GO:0008096)	is_a	epoxide hydrolase activity

EC: 3.3.2.10
MetaCyc: 3.3.2.10-RXN
Reactome: R-HSA-9020257; R-HSA-9025998; R-HSA-9020258; R-HSA-9915968; R-HSA-9020270; R-HSA-9018862; R-HSA-9024890; R-HSA-9020253; R-HSA-2161961; R-HSA-9018877; R-HSA-9020252; R-HSA-9024993; R-HSA-9026008; R-HSA-9024973; R-HSA-9915994; R-HSA-9915986; R-HSA-9026000
RHEA: 19037