AmiGO 2: Term Details for "estradiol 17-beta-dehydrogenase [NAD(P)] activity" (GO:0004303)

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Term Information

Accession: GO:0004303
Name: estradiol 17-beta-dehydrogenase [NAD(P)] activity
Ontology: molecular_function
Synonyms: 17-beta-estradiol dehydrogenase activity, 17beta,20alpha-hydroxysteroid dehydrogenase activity, 17beta-HSD, 17beta-estradiol dehydrogenase activity, 17beta-hydroxysteroid dehydrogenase activity, estradiol 17-beta-dehydrogenase activity, estradiol 17beta-dehydrogenase activity, estradiol dehydrogenase activity, estradiol-17beta:NAD(P)+ 17-oxidoreductase activity, estrogen 17-oxidoreductase activity, 17-beta-HSD activity, 17-beta-hydroxysteroid dehydrogenase activity, 20alpha-hydroxysteroid dehydrogenase
Alternate IDs: None
Definition: Catalysis of the reaction: estradiol-17-beta + NAD(P)+ = estrone + NAD(P)H + H+. The activity can use NAD+ or NADP+ as the acceptor. Source: EC:1.1.1.62
Comment: None
History: See term history for GO:0004303 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to estradiol 17-beta-dehydrogenase [NAD(P)] activity (excluding "regulates").; Link to all direct and indirect annotations to estradiol 17-beta-dehydrogenase [NAD(P)] activity (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for estradiol 17-beta-dehydrogenase [NAD(P)] activity (excluding "regulates").

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GO:0003674 molecular_function
GO:0003824 catalytic activity
GO:0016491 oxidoreductase activity
GO:0016614 oxidoreductase activity, acting on CH-OH group of donors
GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0016229 steroid dehydrogenase activity
GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0004303 estradiol 17-beta-dehydrogenase [NAD(P)] activity

Parents of estradiol 17-beta-dehydrogenase [NAD(P)] activity (GO:0004303)

subject	relation	object
estradiol 17-beta-dehydrogenase [NAD(P)] activity	is_a	steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (GO:0033764)

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EC: 1.1.1.62
MetaCyc: ESTRADIOL-17-BETA-DEHYDROGENASE-RXN
Reactome: R-HSA-5693390; R-HSA-6810594; R-HSA-8862137; R-HSA-804969; R-HSA-5696822
RHEA: 24612; 24616