AmiGO 2: Term Details for "farnesyltranstransferase activity" (GO:0004311)

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Term Information

Accession: GO:0004311
Name: farnesyltranstransferase activity
Ontology: molecular_function
Synonyms: geranylgeranyl pyrophosphate synthase activity, geranylgeranyl pyrophosphate synthetase activity, geranylgeranyl-PP synthetase activity, geranylgeranyl-diphosphate synthase activity, trans,trans-farnesyl-diphosphate:isopentenyl-diphosphate farnesyltranstransferase activity, farnesyltransferase activity
Alternate IDs: None
Definition: Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate + isopentenyl diphosphate = diphosphate + geranylgeranyl diphosphate. Source: EC:2.5.1.29, RHEA:17653
Comment: The catalyzed reaction forms (free) geranylgeranyl diphosphate. There is no relationship between this activity and protein farnesyltransferase activity, GO:0004660, where the catalyzed reaction transfers a farnesyl group from farnesyl diphosphate to a target protein.
History: See term history for GO:0004311 at QuickGO
Chem. react.: has participant 2-trans,6-trans,10-trans-geranylgeranyl diphosphate(3-); has participant diphosphate(3-); has participant 2-trans,6-trans-farnesyl diphosphate(3-); has participant isopentenyl diphosphate(3-)
Subset: None
Related: Link to all genes and gene products annotated to farnesyltranstransferase activity (excluding "regulates").; Link to all direct and indirect annotations to farnesyltranstransferase activity (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for farnesyltranstransferase activity (excluding "regulates").

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For more information, please see the ontology relation documentation.

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Additional internal viewing options

GO:0003674 molecular_function
GO:0003824 catalytic activity
GO:0016740 transferase activity
GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups
GO:0004659 prenyltransferase activity
GO:0004311 farnesyltranstransferase activity

Parents of farnesyltranstransferase activity (GO:0004311)

subject	relation	object
farnesyltranstransferase activity	is_a	prenyltransferase activity (GO:0004659)
farnesyltranstransferase activity	RO:0000057	2-trans,6-trans,10-trans-geranylgeranyl diphosphate(3-) (CHEBI:58756)
farnesyltranstransferase activity	RO:0000057	diphosphate(3-) (CHEBI:33019)
farnesyltranstransferase activity	RO:0000057	2-trans,6-trans-farnesyl diphosphate(3-) (CHEBI:175763)
farnesyltranstransferase activity	RO:0000057	isopentenyl diphosphate(3-) (CHEBI:128769)

This term has no children.

EC: 2.5.1.29
KEGG_REACTION: R02061
MetaCyc: FARNESYLTRANSTRANSFERASE-RXN
RHEA: 17653