Term Information

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Accession
GO:0004325
Name
ferrochelatase activity
Ontology
molecular_function
Synonyms
ferro-protoporphyrin chelatase activity, protoheme ferro-lyase (protoporphyrin-forming), protoheme ferro-lyase activity, protoheme ferrolyase activity, heme synthase activity, heme synthetase activity, iron chelatase activity
Alternate IDs
None
Definition
Catalysis of the reaction: heme B (protoheme) + H+ = Fe(2+) + protoporphyrin IX. Source: RHEA:22584
Comment
None
History
See term history for GO:0004325 at QuickGO
Chem. react.
has participant hydron
has participant iron(2+)
has participant ferroheme b(2-)
has participant protoporphyrin(2-)
Subset
None
Include "regulates"
For more information, please see the ontology relation documentation.

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Graph of GO:0004325 from QuickGO

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Parents of ferrochelatase activity (GO:0004325)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
ferrochelatase activity [RO:0000057 relation] RO:0000057  hydron (CHEBI:15378)
ferrochelatase activity [RO:0000057 relation] RO:0000057  iron(2+) (CHEBI:29033)
ferrochelatase activity [RO:0000057 relation] RO:0000057  ferroheme b(2-) (CHEBI:60344)
ferrochelatase activity [RO:0000057 relation] RO:0000057  protoporphyrin(2-) (CHEBI:57306)
ferrochelatase activity [is_a relation] is_a  lyase activity (GO:0016829)
Children of ferrochelatase activity (GO:0004325)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
regulation of ferrochelatase activity (GO:0010722) [RO:0002211 relation] RO:0002211  ferrochelatase activity
sirohydrochlorin ferrochelatase activity (GO:0051266) [is_a relation] is_a  ferrochelatase activity
EC
4.98.1.1
KEGG_REACTION
R00310
MetaCyc
PROTOHEMEFERROCHELAT-RXN
Reactome
R-HSA-189465
RHEA
22584