AmiGO 2: Term Details for "galactosylceramidase activity" (GO:0004336)

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Term Information

Accession: GO:0004336
Name: galactosylceramidase activity
Ontology: molecular_function
Synonyms: D-galactosyl-N-acylsphingosine galactohydrolase activity, beta-galactocerebrosidase activity, beta-galactosylceramidase activity, ceramide galactosidase activity, cerebroside beta-galactosidase activity, cerebroside galactosidase activity, galactocerebrosidase activity, galactocerebroside beta-galactosidase activity, galactocerebroside galactosidase activity, galactocerebroside-beta-D-galactosidase activity, galactosylceramidase I, galactosylceramide beta-galactosidase activity, galactosylcerebrosidase activity, galcerase activity, lactosylceramidase I, lactosylceramidase activity
Alternate IDs: None
Definition: Catalysis of the reaction: D-galactosyl-N-acylsphingosine + H2O = D-galactose + N-acylsphingosine. Source: EC:3.2.1.46
Comment: None
History: See term history for GO:0004336 at QuickGO
Chem. react.: has participant N-acyl-beta-D-galactosylsphingosine; has participant water; has participant D-galactopyranose; has participant N-acylsphingosine
Subset: None
Related: Link to all genes and gene products annotated to galactosylceramidase activity (excluding "regulates").; Link to all direct and indirect annotations to galactosylceramidase activity (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for galactosylceramidase activity (excluding "regulates").

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For more information, please see the ontology relation documentation.

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GO:0003674 molecular_function
GO:0003824 catalytic activity
GO:0016787 hydrolase activity
GO:0016798 hydrolase activity, acting on glycosyl bonds
GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds
GO:0004336 galactosylceramidase activity

Parents of galactosylceramidase activity (GO:0004336)

subject	relation	object
galactosylceramidase activity	RO:0000057	N-acyl-beta-D-galactosylsphingosine (CHEBI:18390)
galactosylceramidase activity	RO:0000057	water (CHEBI:15377)
galactosylceramidase activity	RO:0000057	D-galactopyranose (CHEBI:4139)
galactosylceramidase activity	is_a	hydrolase activity, hydrolyzing O-glycosyl compounds (GO:0004553)
galactosylceramidase activity	RO:0000057	N-acylsphingosine (CHEBI:52639)

This term has no children.

EC: 3.2.1.46
MetaCyc: GALACTOSYLCERAMIDASE-RXN
Reactome: R-HSA-1606564
RHEA: 14297