AmiGO 2: Term Details for "glucose-6-phosphate dehydrogenase activity" (GO:0004345)

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Term Information

Accession: GO:0004345
Name: glucose-6-phosphate dehydrogenase activity
Ontology: molecular_function
Synonyms: 6-phosphoglucose dehydrogenase activity, D-glucose 6-phosphate dehydrogenase activity, G6PDH, NADP-dependent glucose 6-phosphate dehydrogenase activity, NADP-glucose-6-phosphate dehydrogenase activity, glucose 6-phosphate dehydrogenase (NADP) activity, glucose-6-phosphate 1-dehydrogenase activity, 6-phosphoglucose dehydrogenas, D-glucose-6-phosphate:NADP+ 1-oxidoreductase activity, Entner-doudoroff enzyme, G6PD activity, GDH, Zwischenferment
Alternate IDs: None
Definition: Catalysis of the reaction: D-glucose 6-phosphate + NADP+ = D-glucono-1,5-lactone 6-phosphate + NADPH + H+. Source: EC:1.1.1.49
Comment: None
History: See term history for GO:0004345 at QuickGO
Chem. react.: has participant hydron; has participant NADPH(4-); has participant NADP(3-); has participant 6-O-phosphonato-D-glucono-1,5-lactone(2-); has participant D-glucopyranose 6-phosphate(2-)
Subset: None
Related: Link to all genes and gene products annotated to glucose-6-phosphate dehydrogenase activity (excluding "regulates").; Link to all direct and indirect annotations to glucose-6-phosphate dehydrogenase activity (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for glucose-6-phosphate dehydrogenase activity (excluding "regulates").

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GO:0003674 molecular_function
GO:0003824 catalytic activity
GO:0016491 oxidoreductase activity
GO:0016614 oxidoreductase activity, acting on CH-OH group of donors
GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0004345 glucose-6-phosphate dehydrogenase activity

Parents of glucose-6-phosphate dehydrogenase activity (GO:0004345)

subject	relation	object
glucose-6-phosphate dehydrogenase activity	RO:0000057	hydron (CHEBI:15378)
glucose-6-phosphate dehydrogenase activity	RO:0000057	NADPH(4-) (CHEBI:57783)
glucose-6-phosphate dehydrogenase activity	RO:0000057	NADP(3-) (CHEBI:58349)
glucose-6-phosphate dehydrogenase activity	RO:0000057	6-O-phosphonato-D-glucono-1,5-lactone(2-) (CHEBI:57955)
glucose-6-phosphate dehydrogenase activity	is_a	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (GO:0016616)
glucose-6-phosphate dehydrogenase activity	RO:0000057	D-glucopyranose 6-phosphate(2-) (CHEBI:61548)

This term has no children.

EC: 1.1.1.49
MetaCyc: GLU6PDEHYDROG-RXN
Reactome: R-HSA-70377
RHEA: 15841