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glutamate synthase (NADPH) activity

Term Information

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Accession
GO:0004355
Name
glutamate synthase (NADPH) activity
Ontology
molecular_function
Synonyms
NADPH GOGAT, L-glutamate:NADP+ oxidoreductase (transaminating), L-glutamine:2-oxoglutarate aminotransferase, NADPH oxidizing activity, NADPH-dependent glutamate synthase activity, NADPH-glutamate synthase activity, NADPH-linked glutamate synthase, glutamate (reduced nicotinamide adenine dinucleotide phosphate) synthase activity, glutamate synthetase (NADP) activity, glutamine amide-2-oxoglutarate aminotransferase (oxidoreductase, NADP) activity, glutamine-ketoglutaric aminotransferase activity, GOGAT activity, L-glutamate synthase activity, L-glutamate synthetase activity
Alternate IDs
None
Definition
Catalysis of the reaction: 2 L-glutamate + NADP+ = 2-oxoglutarate + L-glutamine + H+ + NADPH. This is a two-step reaction: (a) L-glutamate + NH3 = L-glutamine + H2O, (b) L-glutamate + NADP+ + H2O = NH3 + 2-oxoglutarate + NADPH + H+. Source: RHEA:15501, EC:1.4.1.13
Comment
Note that this term has a MetaCyc pathway reference as the pathway only has a single step.
History
See term history for GO:0004355 at QuickGO
Chem. react.
has participant 2-oxoglutarate(2-)
has participant L-glutamate(1-)
has participant NADPH(4-)
has participant L-glutamine zwitterion
has participant NADP(3-)
has participant hydron
Subset
None
Include "regulates"
For more information, please see the ontology relation documentation.

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Parents of glutamate synthase (NADPH) activity (GO:0004355)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
glutamate synthase (NADPH) activity [RO:0000057 relation] RO:0000057  2-oxoglutarate(2-) (CHEBI:16810)
glutamate synthase (NADPH) activity [RO:0000057 relation] RO:0000057  L-glutamate(1-) (CHEBI:29985)
glutamate synthase (NADPH) activity [is_a relation] is_a  glutamate synthase activity, NAD(P)H as acceptor (GO:0045181)
glutamate synthase (NADPH) activity [RO:0000057 relation] RO:0000057  NADPH(4-) (CHEBI:57783)
glutamate synthase (NADPH) activity [RO:0000057 relation] RO:0000057  L-glutamine zwitterion (CHEBI:58359)
glutamate synthase (NADPH) activity [RO:0000057 relation] RO:0000057  NADP(3-) (CHEBI:58349)
glutamate synthase (NADPH) activity [RO:0000057 relation] RO:0000057  hydron (CHEBI:15378)
Children of glutamate synthase (NADPH) activity (GO:0004355)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
glutamine catabolic process to fumarate, using glutamate synthase (NADPH) (GO:0019461) [BFO:0000051 relation] BFO:0000051  glutamate synthase (NADPH) activity
glutamate synthase complex (NADPH) (GO:0009342) [RO:0002215 relation] RO:0002215  glutamate synthase (NADPH) activity