Term Information

Feedback 
Accession
GO:0004375
Name
glycine dehydrogenase (decarboxylating) activity
Ontology
molecular_function
Synonyms
glycine decarboxylase activity, glycine-cleavage complex, glycine-cleavage complex P-protein activity, glycine:H-protein-lipoyllysine oxidoreductase (decarboxylating, acceptor-amino-methylating), glycine:lipoylprotein oxidoreductase (decarboxylating and acceptor-aminomethylating), P-protein, glycine cleavage system P-protein activity, protein P1
Alternate IDs
None
Definition
Catalysis of the reaction: glycine + lipoylprotein = S-aminomethyldihydrolipoylprotein + CO2. Source: EC:1.4.4.2
Comment
None
History
See term history for GO:0004375 at QuickGO
Chem. react.
has participant N(6)-[(R)-lipoyl]-L-lysine residue
has participant N(6)-[(R)-S(8)-ammoniomethyldihydrolipoyl]-L-lysine(1+) residue
has participant glycine zwitterion
has participant carbon dioxide
has participant hydron
Subset
None
Include "regulates"
For more information, please see the ontology relation documentation.

Filter results

Loading...
pending...
View this term in QuickGO.

Graph of GO:0004375 from QuickGO

Additional external viewing options
Additional internal viewing options
Parents of glycine dehydrogenase (decarboxylating) activity (GO:0004375)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
glycine dehydrogenase (decarboxylating) activity [RO:0000057 relation] RO:0000057  N(6)-[(R)-lipoyl]-L-lysine residue (CHEBI:83099)
glycine dehydrogenase (decarboxylating) activity [RO:0000057 relation] RO:0000057  N(6)-[(R)-S(8)-ammoniomethyldihydrolipoyl]-L-lysine(1+) residue (CHEBI:83143)
glycine dehydrogenase (decarboxylating) activity [RO:0000057 relation] RO:0000057  glycine zwitterion (CHEBI:57305)
glycine dehydrogenase (decarboxylating) activity [RO:0000057 relation] RO:0000057  carbon dioxide (CHEBI:16526)
glycine dehydrogenase (decarboxylating) activity [RO:0000057 relation] RO:0000057  hydron (CHEBI:15378)
glycine dehydrogenase (decarboxylating) activity [is_a relation] is_a  oxidoreductase activity, acting on the CH-NH2 group of donors, disulfide as acceptor (GO:0016642)
Children of glycine dehydrogenase (decarboxylating) activity (GO:0004375)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
glycine cleavage complex (GO:0005960) [RO:0002215 relation] RO:0002215  glycine dehydrogenase (decarboxylating) activity
EC
1.4.4.2
MetaCyc
GCVP-RXN
Reactome
R-HSA-5693967
RHEA
24304