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GDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase activity

Term Information

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Accession
GO:0004377
Name
GDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase activity
Ontology
molecular_function
Synonyms
GDP-D-mannose:D-Man-alpha-(1->3)-[D-Man-alpha-(1->6)]-D-Man-beta-(1->4)-D-GlcNAc-beta-(1->4)-D-GlcNAc-diphosphodolichol alpha-1,2-mannosyltransferase activity, GDP-mannose-oligosaccharide-lipid mannosyltransferase activity, GDP-mannose:glycolipid 1,2-alpha-D-mannosyltransferase activity, glycolipid 2-alpha-mannosyltransferase activity, guanosine diphosphomannose-oligosaccharide-lipid mannosyltransferase activity, oligosaccharide-lipid mannosyltransferase activity
Alternate IDs
None
Definition
Catalysis of the reaction: an alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc-diphosphodolichol + 2 GDP-alpha-D-mannose = an alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc-diphosphodolichol + 2 GDP + 2 H+. This reaction is the transfer of an alpha-D-mannosyl residue from GDP-mannose into lipid-linked oligosaccharide, forming an alpha-(1->2)-D-mannosyl-D-mannose linkage. Source: EC:2.4.1.131
Comment
None
History
See term history for GO:0004377 at QuickGO
Chem. react.
has participant GDP-alpha-D-mannose(2-)
has participant hydron
has participant GDP(3-)
has participant alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc(PP-Dol)(2-)
has participant alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc(PP-Dol)(2-)
Subset
None
Include "regulates"
For more information, please see the ontology relation documentation.

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Parents of GDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase activity (GO:0004377)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
GDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase activity [RO:0000057 relation] RO:0000057  GDP-alpha-D-mannose(2-) (CHEBI:57527)
GDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase activity [RO:0000057 relation] RO:0000057  hydron (CHEBI:15378)
GDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase activity [is_a relation] is_a  alpha-1,2-mannosyltransferase activity (GO:0000026)
GDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase activity [RO:0000057 relation] RO:0000057  GDP(3-) (CHEBI:58189)
GDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase activity [RO:0000057 relation] RO:0000057  alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc(PP-Dol)(2-) (CHEBI:132511)
GDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase activity [is_a relation] is_a  glycolipid mannosyltransferase activity (GO:0004376)
GDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase activity [RO:0000057 relation] RO:0000057  alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc(PP-Dol)(2-) (CHEBI:132515)

This term has no children.

EC
2.4.1.131
MetaCyc
RXN-5464
RHEA
29523