Term Information

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Accession
GO:0004378
Name
GDP-Man:Man1GlcNAc2-PP-Dol alpha-1,3-mannosyltransferase activity
Ontology
molecular_function
Synonyms
GDP-D-mannose:D-Man-beta-(1->4)-D-GlcNAc-beta-(1->4)-D-GlcNAc-diphosphodolichol 3-alpha-mannosyltransferase activity, GDP-mannose-oligosaccharide-lipid mannosyltransferase II, GDP-mannose:glycolipid 1,3-alpha-D-mannosyltransferase activity, glycolipid 3-alpha-mannosyltransferase activity, guanosine diphosphomannose-oligosaccharide-lipid II mannosyltransferase activity, mannosyltransferase II activity
Alternate IDs
None
Definition
Catalysis of the reaction: beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc-diphosphodolichol + GDP-alpha-D-mannose = alpha-D-Man-(1->3)-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc-diphosphodolichol + GDP + H+. This reaction is the transfer of an alpha-D-mannosyl residue from GDP-mannose into lipid-linked oligosaccharide, forming an alpha-(1->3)-D-mannosyl-D-mannose linkage. Source: EC:2.4.1.132
Comment
None
History
See term history for GO:0004378 at QuickGO
Chem. react.
has participant hydron
has participant alpha-D-Man-(1->3)-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc(PP-Dol)(2-)
has participant GDP-alpha-D-mannose(2-)
has participant GDP(3-)
has participant beta-D-mannosyldiacetylchitobiosyldiphosphodolichol(2-)
Subset
None
Include "regulates"
For more information, please see the ontology relation documentation.

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Graph of GO:0004378 from QuickGO

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Parents of GDP-Man:Man1GlcNAc2-PP-Dol alpha-1,3-mannosyltransferase activity (GO:0004378)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
GDP-Man:Man1GlcNAc2-PP-Dol alpha-1,3-mannosyltransferase activity [RO:0000057 relation] RO:0000057  hydron (CHEBI:15378)
GDP-Man:Man1GlcNAc2-PP-Dol alpha-1,3-mannosyltransferase activity [RO:0000057 relation] RO:0000057  alpha-D-Man-(1->3)-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc(PP-Dol)(2-) (CHEBI:132510)
GDP-Man:Man1GlcNAc2-PP-Dol alpha-1,3-mannosyltransferase activity [is_a relation] is_a  glycolipid mannosyltransferase activity (GO:0004376)
GDP-Man:Man1GlcNAc2-PP-Dol alpha-1,3-mannosyltransferase activity [RO:0000057 relation] RO:0000057  GDP-alpha-D-mannose(2-) (CHEBI:57527)
GDP-Man:Man1GlcNAc2-PP-Dol alpha-1,3-mannosyltransferase activity [RO:0000057 relation] RO:0000057  GDP(3-) (CHEBI:58189)
GDP-Man:Man1GlcNAc2-PP-Dol alpha-1,3-mannosyltransferase activity [RO:0000057 relation] RO:0000057  beta-D-mannosyldiacetylchitobiosyldiphosphodolichol(2-) (CHEBI:58472)

This term has no children.

EC
2.4.1.132
MetaCyc
RXN-5462
RHEA
29515