Term Information

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Accession
GO:0004383
Name
guanylate cyclase activity
Ontology
molecular_function
Synonyms
guanylyl cyclase activity, GTP diphosphate-lyase (cyclizing) activity, GTP diphosphate-lyase (cyclizing; 3',5'-cyclic-GMP-forming) activity, guanyl cyclase activity, receptor guanylate cyclase activity
Alternate IDs
None
Definition
Catalysis of the reaction: GTP = 3',5'-cyclic GMP + diphosphate. Source: EC:4.6.1.2
Comment
None
History
See term history for GO:0004383 at QuickGO
Chem. react.
has participant diphosphate(3-)
has participant GTP(4-)
has participant 3',5'-cyclic GMP(1-)
Subset
None
Include "regulates"
For more information, please see the ontology relation documentation.

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Graph of GO:0004383 from QuickGO

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Parents of guanylate cyclase activity (GO:0004383)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
guanylate cyclase activity [RO:0000057 relation] RO:0000057  diphosphate(3-) (CHEBI:33019)
guanylate cyclase activity [is_a relation] is_a  cyclase activity (GO:0009975)
guanylate cyclase activity [BFO:0000050 relation] BFO:0000050  cGMP biosynthetic process (GO:0006182)
guanylate cyclase activity [RO:0000057 relation] RO:0000057  GTP(4-) (CHEBI:37565)
guanylate cyclase activity [RO:0000057 relation] RO:0000057  3',5'-cyclic GMP(1-) (CHEBI:57746)
guanylate cyclase activity [is_a relation] is_a  phosphorus-oxygen lyase activity (GO:0016849)
Children of guanylate cyclase activity (GO:0004383)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
regulation of guanylate cyclase activity (GO:0031282) [RO:0002211 relation] RO:0002211  guanylate cyclase activity
guanylate cyclase regulator activity (GO:0030249) [RO:0002578 relation] RO:0002578  guanylate cyclase activity
positive regulation of guanylate cyclase activity (GO:0031284) [RO:0002213 relation] RO:0002213  guanylate cyclase activity
negative regulation of guanylate cyclase activity (GO:0031283) [RO:0002212 relation] RO:0002212  guanylate cyclase activity
guanylate cyclase activator activity (GO:0030250) [RO:0002629 relation] RO:0002629  guanylate cyclase activity
guanylate cyclase inhibitor activity (GO:0030251) [RO:0002630 relation] RO:0002630  guanylate cyclase activity