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heme oxygenase (decyclizing) activity

Term Information

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Accession
GO:0004392
Name
heme oxygenase (decyclizing) activity
Ontology
molecular_function
Synonyms
haem oxygenase (decyclizing) activity, ORP33 proteins, haem oxidase activity, haem oxygenase activity, heme oxidase activity, heme oxygenase activity, heme,hydrogen-donor:oxygen oxidoreductase (alpha-methene-oxidizing, hydroxylating)
Alternate IDs
None
Definition
Catalysis of the reaction: heme b + 3 O2 + 3 reduced [NADPH-hemoprotein reductase] = biliverdin + CO + Fe2+ + H+ + 3 H2O + 3 oxidized [NADPH-hemoprotein reductase]. Source: RHEA:21764
Comment
None
History
See term history for GO:0004392 at QuickGO
Chem. react.
has participant FMNH2(2-)
has participant hydron
has participant water
has participant dioxygen
has participant FMN(3-)
has participant ferroheme b(2-)
has participant biliverdin(2-)
has participant iron(2+)
has participant carbon monoxide
Subset
None
Include "regulates"
For more information, please see the ontology relation documentation.

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Graph of GO:0004392 from QuickGO

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Parents of heme oxygenase (decyclizing) activity (GO:0004392)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
heme oxygenase (decyclizing) activity [RO:0000057 relation] RO:0000057  FMNH2(2-) (CHEBI:57618)
heme oxygenase (decyclizing) activity [RO:0000057 relation] RO:0000057  hydron (CHEBI:15378)
heme oxygenase (decyclizing) activity [RO:0000057 relation] RO:0000057  water (CHEBI:15377)
heme oxygenase (decyclizing) activity [is_a relation] is_a  oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen (GO:0016712)
heme oxygenase (decyclizing) activity [RO:0000057 relation] RO:0000057  dioxygen (CHEBI:15379)
heme oxygenase (decyclizing) activity [RO:0000057 relation] RO:0000057  FMN(3-) (CHEBI:58210)
heme oxygenase (decyclizing) activity [RO:0000057 relation] RO:0000057  ferroheme b(2-) (CHEBI:60344)
heme oxygenase (decyclizing) activity [RO:0000057 relation] RO:0000057  biliverdin(2-) (CHEBI:57991)
heme oxygenase (decyclizing) activity [RO:0000057 relation] RO:0000057  iron(2+) (CHEBI:29033)
heme oxygenase (decyclizing) activity [RO:0000057 relation] RO:0000057  carbon monoxide (CHEBI:17245)
Children of heme oxygenase (decyclizing) activity (GO:0004392)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
negative regulation of heme oxygenase activity (GO:0061962) [RO:0002212 relation] RO:0002212  heme oxygenase (decyclizing) activity
regulation of heme oxygenase activity (GO:0061960) [RO:0002211 relation] RO:0002211  heme oxygenase (decyclizing) activity
positive regulation of heme oxygenase activity (GO:0061961) [RO:0002213 relation] RO:0002213  heme oxygenase (decyclizing) activity