AmiGO 2: Term Details for "homogentisate 1,2-dioxygenase activity" (GO:0004411)

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Term Information

Accession: GO:0004411
Name: homogentisate 1,2-dioxygenase activity
Ontology: molecular_function
Synonyms: homogentisate dioxygenase activity, homogentisate oxidase activity, homogentisate oxygenase activity, homogentisate:oxygen 1,2-oxidoreductase (decyclizing), homogentisic acid oxidase activity, homogentisic acid oxygenase activity, homogentisic oxygenase activity, homogentisicase activity
Alternate IDs: None
Definition: Catalysis of the reaction: homogentisate + O2 = 4-maleylacetoacetate + H+. Source: EC:1.13.11.5, RHEA:15449
Comment: None
History: See term history for GO:0004411 at QuickGO
Chem. react.: has participant hydron; has participant homogentisate; has participant 4-maleylacetoacetate; has participant dioxygen
Subset: None
Related: Link to all genes and gene products annotated to homogentisate 1,2-dioxygenase activity (excluding "regulates").; Link to all direct and indirect annotations to homogentisate 1,2-dioxygenase activity (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for homogentisate 1,2-dioxygenase activity (excluding "regulates").

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For more information, please see the ontology relation documentation.

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GO:0003674 molecular_function
GO:0003824 catalytic activity
GO:0016491 oxidoreductase activity
GO:0051213 dioxygenase activity
GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen
GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
GO:0004411 homogentisate 1,2-dioxygenase activity

Parents of homogentisate 1,2-dioxygenase activity (GO:0004411)

subject	relation	object
homogentisate 1,2-dioxygenase activity	RO:0000057	hydron (CHEBI:15378)
homogentisate 1,2-dioxygenase activity	is_a	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen (GO:0016702)
homogentisate 1,2-dioxygenase activity	RO:0000057	homogentisate (CHEBI:16169)
homogentisate 1,2-dioxygenase activity	RO:0000057	4-maleylacetoacetate (CHEBI:17105)
homogentisate 1,2-dioxygenase activity	RO:0000057	dioxygen (CHEBI:15379)

This term has no children.

EC: 1.13.11.5
KEGG_REACTION: R02519
MetaCyc: HOMOGENTISATE-12-DIOXYGENASE-RXN
Reactome: R-HSA-71164
RHEA: 15449
UM-BBD_reactionID: r0105