Term Information

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Accession
GO:0004416
Name
hydroxyacylglutathione hydrolase activity
Ontology
molecular_function
Synonyms
S-(2-hydroxyacyl)glutathione hydrolase activity, S-2-hydroxylacylglutathione hydrolase activity, acetoacetylglutathione hydrolase activity, glyoxalase II activity
Alternate IDs
None
Definition
Catalysis of the reaction: (S)-(2-hydroxyacyl)glutathione + H2O = glutathione + a 2-hydroxy carboxylate. Source: EC:3.1.2.6
Comment
None
History
See term history for GO:0004416 at QuickGO
Chem. react.
has participant glutathionate(1-)
has participant (R)-S-lactoylglutathionate(1-)
has participant water
has participant hydron
has participant (R)-lactate
Subset
None
Include "regulates"
For more information, please see the ontology relation documentation.

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Graph of GO:0004416 from QuickGO

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Parents of hydroxyacylglutathione hydrolase activity (GO:0004416)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
hydroxyacylglutathione hydrolase activity [RO:0000057 relation] RO:0000057  glutathionate(1-) (CHEBI:57925)
hydroxyacylglutathione hydrolase activity [RO:0000057 relation] RO:0000057  (R)-S-lactoylglutathionate(1-) (CHEBI:57474)
hydroxyacylglutathione hydrolase activity [is_a relation] is_a  thiolester hydrolase activity (GO:0016790)
hydroxyacylglutathione hydrolase activity [RO:0000057 relation] RO:0000057  water (CHEBI:15377)
hydroxyacylglutathione hydrolase activity [RO:0000057 relation] RO:0000057  hydron (CHEBI:15378)
hydroxyacylglutathione hydrolase activity [RO:0000057 relation] RO:0000057  (R)-lactate (CHEBI:16004)

This term has no children.

EC
3.1.2.6
MetaCyc
GLYOXII-RXN
Reactome
R-HSA-6783221
RHEA
25245