Term Information

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Accession
GO:0004422
Name
hypoxanthine phosphoribosyltransferase activity
Ontology
molecular_function
Synonyms
6-hydroxypurine phosphoribosyltransferase activity, 6-mercaptopurine phosphoribosyltransferase activity, HGPRTase activity, HPRT, IMP diphosphorylase activity, IMP pyrophosphorylase activity, IMP-GMP pyrophosphorylase activity, IMP:diphosphate phospho-D-ribosyltransferase activity, inosinate pyrophosphorylase activity, inosine 5'-phosphate pyrophosphorylase activity, inosinic acid pyrophosphorylase activity, inosinic pyrophosphorylase activity, purine-6-thiol phosphoribosyltransferase activity, Transphosphoribosidase activity, guanine-hypoxanthine phosphoribosyltransferase activity, hypoxanthine-guanine phosphoribosyltransferase activity
Alternate IDs
None
Definition
Catalysis of the reaction: IMP + diphosphate = hypoxanthine + 5-phospho-alpha-D-ribose 1-diphosphate. Source: EC:2.4.2.8, GOC:curators
Comment
None
History
See term history for GO:0004422 at QuickGO
Chem. react.
has participant hypoxanthine
has participant 5-O-phosphonato-alpha-D-ribofuranosyl diphosphate(5-)
has participant diphosphate(3-)
has participant IMP(2-)
Subset
None
Include "regulates"
For more information, please see the ontology relation documentation.

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Graph of GO:0004422 from QuickGO

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Parents of hypoxanthine phosphoribosyltransferase activity (GO:0004422)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
hypoxanthine phosphoribosyltransferase activity [RO:0000057 relation] RO:0000057  hypoxanthine (CHEBI:17368)
hypoxanthine phosphoribosyltransferase activity [is_a relation] is_a  purine phosphoribosyltransferase activity (GO:0106130)
hypoxanthine phosphoribosyltransferase activity [RO:0000057 relation] RO:0000057  5-O-phosphonato-alpha-D-ribofuranosyl diphosphate(5-) (CHEBI:58017)
hypoxanthine phosphoribosyltransferase activity [RO:0000057 relation] RO:0000057  diphosphate(3-) (CHEBI:33019)
hypoxanthine phosphoribosyltransferase activity [RO:0000057 relation] RO:0000057  IMP(2-) (CHEBI:58053)

This term has no children.

EC
2.4.2.8
KEGG_REACTION
R01132
MetaCyc
HYPOXANPRIBOSYLTRAN-RXN
RHEA
17973