AmiGO 2: Term Details for "indole-3-glycerol-phosphate synthase activity" (GO:0004425)

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Term Information

Accession: GO:0004425
Name: indole-3-glycerol-phosphate synthase activity
Ontology: molecular_function
Synonyms: 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose-5-phosphate carboxy-lyase (cyclizing), 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose-5-phosphate carboxy-lyase [cyclizing; 1-C-(3-indolyl)-glycerol-3-phosphate-forming], indole-3-glycerophosphate synthase activity, indoleglycerol phosphate synthase activity, indoleglycerol phosphate synthetase activity
Alternate IDs: None
Definition: Catalysis of the reaction: 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate = 1-(indol-3-yl)glycerol 3-phosphate + CO2 + H2O. Source: EC:4.1.1.48
Comment: None
History: See term history for GO:0004425 at QuickGO
Chem. react.: has participant (1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate(2-); has participant water; has participant 1-(2-carboxylatophenylamino)-1-deoxy-D-ribulose 5-phosphate(3-); has participant hydron; has participant carbon dioxide
Subset: None
Related: Link to all genes and gene products annotated to indole-3-glycerol-phosphate synthase activity (excluding "regulates").; Link to all direct and indirect annotations to indole-3-glycerol-phosphate synthase activity (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for indole-3-glycerol-phosphate synthase activity (excluding "regulates").

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GO:0003674 molecular_function
GO:0003824 catalytic activity
GO:0016829 lyase activity
GO:0016830 carbon-carbon lyase activity
GO:0016831 carboxy-lyase activity
GO:0004425 indole-3-glycerol-phosphate synthase activity

Parents of indole-3-glycerol-phosphate synthase activity (GO:0004425)

subject	relation	object
indole-3-glycerol-phosphate synthase activity	is_a	carboxy-lyase activity (GO:0016831)
indole-3-glycerol-phosphate synthase activity	RO:0000057	(1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate(2-) (CHEBI:58866)
indole-3-glycerol-phosphate synthase activity	RO:0000057	water (CHEBI:15377)
indole-3-glycerol-phosphate synthase activity	RO:0000057	1-(2-carboxylatophenylamino)-1-deoxy-D-ribulose 5-phosphate(3-) (CHEBI:58613)
indole-3-glycerol-phosphate synthase activity	RO:0000057	hydron (CHEBI:15378)
indole-3-glycerol-phosphate synthase activity	RO:0000057	carbon dioxide (CHEBI:16526)

This term has no children.

EC: 4.1.1.48
MetaCyc: IGPSYN-RXN
RHEA: 23476