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phosphatidylinositol phospholipase C activity

Term Information

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Accession
GO:0004435
Name
phosphatidylinositol phospholipase C activity
Ontology
molecular_function
Synonyms
1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase activity, 1-phosphatidyl-1D-myo-inositol-4,5-bisphosphate inositoltrisphosphohydrolase activity, 1-phosphatidyl-D-myo-inositol-4,5-bisphosphate inositoltrisphosphohydrolase activity, PI-PLC activity, phosphatidylinositol-4,5-bisphosphate hydrolysis, phosphoinositidase C activity, phosphoinositide phospholipase C activity, monophosphatidylinositol phosphodiesterase activity, triphosphoinositide phosphodiesterase activity
Alternate IDs
None
Definition
Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H2O = 1,2-diacylglycerol + 1D-myo-inositol 1,4,5-trisphosphate + H+. Source: RHEA:33179, EC:3.1.4.11
Comment
None
History
See term history for GO:0004435 at QuickGO
Chem. react.
has participant hydron
has participant 1,2-diacyl-sn-glycerol
has participant 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate(5-)
has participant 1D-myo-inositol 1,4,5-trisphosphate(6-)
has participant water
Subset
None
Include "regulates"
For more information, please see the ontology relation documentation.

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Graph of GO:0004435 from QuickGO

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Parents of phosphatidylinositol phospholipase C activity (GO:0004435)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
phosphatidylinositol phospholipase C activity [is_a relation] is_a  phospholipase C activity (GO:0004629)
phosphatidylinositol phospholipase C activity [RO:0000057 relation] RO:0000057  hydron (CHEBI:15378)
phosphatidylinositol phospholipase C activity [RO:0000057 relation] RO:0000057  1,2-diacyl-sn-glycerol (CHEBI:17815)
phosphatidylinositol phospholipase C activity [RO:0000057 relation] RO:0000057  1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate(5-) (CHEBI:58456)
phosphatidylinositol phospholipase C activity [RO:0000057 relation] RO:0000057  1D-myo-inositol 1,4,5-trisphosphate(6-) (CHEBI:203600)
phosphatidylinositol phospholipase C activity [RO:0000057 relation] RO:0000057  water (CHEBI:15377)

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