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ketol-acid reductoisomerase activity

Term Information

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Accession
GO:0004455
Name
ketol-acid reductoisomerase activity
Ontology
molecular_function
Synonyms
(R)-2,3-dihydroxy-3-methylbutanoate:NADP+ oxidoreductase (isomerizing), 2-hydroxy-3-keto acid reductoisomerase activity, acetohydroxy acid isomeroreductase activity, acetohydroxy acid reductoisomerase activity, acetolactate reductoisomerase activity, alpha-keto-beta-hydroxylacyl reductoisomerase activity, dihydroxyisovalerate (isomerizing) dehydrogenase activity, dihydroxyisovalerate dehydrogenase (isomerizing) activity, isomeroreductase activity, ketol acid reductoisomerase activity, reductoisomerase activity
Alternate IDs
None
Definition
Catalysis of the reaction: (R)-2,3-dihydroxy-3-methylbutanoate + NADP+ = (S)-2-hydroxy-2-methyl-3-oxobutanoate + NADPH + H+. Source: EC:1.1.1.86
Comment
None
History
See term history for GO:0004455 at QuickGO
Chem. react.
has participant NADPH(4-)
has participant NADP(3-)
has participant (2S)-2-hydroxy-2-methyl-3-oxobutanoate
has participant (R)-2,3-dihydroxy-3-methylbutanoate
has participant hydron
Subset
None
Include "regulates"
For more information, please see the ontology relation documentation.

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Parents of ketol-acid reductoisomerase activity (GO:0004455)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
ketol-acid reductoisomerase activity [RO:0000057 relation] RO:0000057  NADPH(4-) (CHEBI:57783)
ketol-acid reductoisomerase activity [RO:0000057 relation] RO:0000057  NADP(3-) (CHEBI:58349)
ketol-acid reductoisomerase activity [RO:0000057 relation] RO:0000057  (2S)-2-hydroxy-2-methyl-3-oxobutanoate (CHEBI:58476)
ketol-acid reductoisomerase activity [RO:0000057 relation] RO:0000057  (R)-2,3-dihydroxy-3-methylbutanoate (CHEBI:49072)
ketol-acid reductoisomerase activity [is_a relation] is_a  oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (GO:0016616)
ketol-acid reductoisomerase activity [RO:0000057 relation] RO:0000057  hydron (CHEBI:15378)

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