Term Information

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Accession
GO:0004462
Name
lactoylglutathione lyase activity
Ontology
molecular_function
Synonyms
(R)-S-lactoylglutathione methylglyoxal-lyase (isomerizing) activity, (R)-S-lactoylglutathione methylglyoxal-lyase (isomerizing; glutathione-forming), aldoketomutase activity, glyoxalase I activity, glyoxylase I, ketone-aldehyde mutase activity, methylglyoxalase activity
Alternate IDs
None
Definition
Catalysis of the reaction: (R)-S-lactoylglutathione = glutathione + methylglyoxal. Source: RHEA:19069, EC:4.4.1.5
Comment
None
History
See term history for GO:0004462 at QuickGO
Chem. react.
has participant methylglyoxal
has participant glutathionate(1-)
has participant (R)-S-lactoylglutathionate(1-)
Subset
None
Include "regulates"
For more information, please see the ontology relation documentation.

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Graph of GO:0004462 from QuickGO

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Parents of lactoylglutathione lyase activity (GO:0004462)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
lactoylglutathione lyase activity [is_a relation] is_a  carbon-sulfur lyase activity (GO:0016846)
lactoylglutathione lyase activity [RO:0000057 relation] RO:0000057  methylglyoxal (CHEBI:17158)
lactoylglutathione lyase activity [RO:0000057 relation] RO:0000057  glutathionate(1-) (CHEBI:57925)
lactoylglutathione lyase activity [RO:0000057 relation] RO:0000057  (R)-S-lactoylglutathionate(1-) (CHEBI:57474)

This term has no children.

EC
4.4.1.5
KEGG_REACTION
R02530
MetaCyc
GLYOXI-RXN
Reactome
R-HSA-5694071
RHEA
19069