Term Information

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Accession
GO:0004463
Name
leukotriene-A4 hydrolase activity
Ontology
molecular_function
Synonyms
(7E,9E,11Z,14Z)-(5S,6S)-5,6-epoxyicosa-7,9,11,14-tetraenoate hydrolase activity, LTA-4 hydrolase activity, LTA4 hydrolase activity, LTA4H, leukotriene A(4) hydrolase activity, leukotriene A4 hydrolase activity
Alternate IDs
None
Definition
Catalysis of the reaction: H2O + leukotriene A(4) = leukotriene B(4). Source: RHEA:22324, EC:3.3.2.6
Comment
None
History
See term history for GO:0004463 at QuickGO
Chem. react.
has participant leukotriene B4(1-)
has participant water
has participant leukotriene A4(1-)
Subset
None
Include "regulates"
For more information, please see the ontology relation documentation.

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Graph of GO:0004463 from QuickGO

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Parents of leukotriene-A4 hydrolase activity (GO:0004463)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
leukotriene-A4 hydrolase activity [RO:0000057 relation] RO:0000057  leukotriene B4(1-) (CHEBI:57461)
leukotriene-A4 hydrolase activity [is_a relation] is_a  ether hydrolase activity (GO:0016803)
leukotriene-A4 hydrolase activity [RO:0000057 relation] RO:0000057  water (CHEBI:15377)
leukotriene-A4 hydrolase activity [RO:0000057 relation] RO:0000057  leukotriene A4(1-) (CHEBI:57463)
Children of leukotriene-A4 hydrolase activity (GO:0004463)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
isochorismatase activity (GO:0008908) [is_a relation] is_a  leukotriene-A4 hydrolase activity
EC
3.3.2.6
KEGG_REACTION
R03057
MetaCyc
LEUKOTRIENE-A4-HYDROLASE-RXN
Reactome
R-HSA-266072
RHEA
22324