AmiGO 2: Term Details for "malate dehydrogenase (decarboxylating) (NADP+) activity" (GO:0004473)

Accession: GO:0004473
Name: malate dehydrogenase (decarboxylating) (NADP+) activity
Ontology: molecular_function
Synonyms: 'malic' enzyme, (S)-malate:NADP+ oxidoreductase (oxaloacetate-decarboxylating), L-malate:NADP oxidoreductase activity, NADP-linked decarboxylating malic enzyme, NADP-malic enzyme activity, NADP-specific malate dehydrogenase activity, NADP-specific malic enzyme, malate dehydrogenase (NADP, decarboxylating), malate dehydrogenase (decarboxylating, NADP)
Alternate IDs: None
Definition: Catalysis of the reaction: (S)-malate + NADP+ = pyruvate + CO2 + NADPH + H+. Source: EC:1.1.1.40
Comment: For decarboxylation of oxaloacetate (the second substrate listed in EC:1.1.1.40), see 'oxaloacetate decarboxylase activity ; GO:0008948'.
History: See term history for GO:0004473 at QuickGO
Chem. react.: has participant carbon dioxide; has participant NADP(3-); has participant NADPH(4-); has participant (S)-malate(2-); has participant pyruvate
Subset: None
Related: Link to all genes and gene products annotated to malate dehydrogenase (decarboxylating) (NADP+) activity (excluding "regulates").; Link to all direct and indirect annotations to malate dehydrogenase (decarboxylating) (NADP+) activity (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for malate dehydrogenase (decarboxylating) (NADP+) activity (excluding "regulates").

Include "regulates"
For more information, please see the ontology relation documentation.

subject	relation	object
malate dehydrogenase (decarboxylating) (NADP+) activity	RO:0000057	carbon dioxide (CHEBI:16526)
malate dehydrogenase (decarboxylating) (NADP+) activity	RO:0000057	NADP(3-) (CHEBI:58349)
malate dehydrogenase (decarboxylating) (NADP+) activity	RO:0000057	NADPH(4-) (CHEBI:57783)
malate dehydrogenase (decarboxylating) (NADP+) activity	is_a	malic enzyme activity (GO:0004470)
malate dehydrogenase (decarboxylating) (NADP+) activity	RO:0000057	(S)-malate(2-) (CHEBI:15589)
malate dehydrogenase (decarboxylating) (NADP+) activity	RO:0000057	pyruvate (CHEBI:15361)
malate dehydrogenase (decarboxylating) (NADP+) activity	is_a	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (GO:0016616)

subject	relation	object
regulation of malate dehydrogenase (decarboxylating) (NADP+) activity (GO:1903218)	RO:0002211	malate dehydrogenase (decarboxylating) (NADP+) activity
positive regulation of malate dehydrogenase (decarboxylating) (NADP+) activity (GO:1903220)	RO:0002213	malate dehydrogenase (decarboxylating) (NADP+) activity
negative regulation of malate dehydrogenase (decarboxylating) (NADP+) activity (GO:1903219)	RO:0002212	malate dehydrogenase (decarboxylating) (NADP+) activity