AmiGO 2: Term Details for "malate synthase activity" (GO:0004474)

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Term Information

Accession: GO:0004474
Name: malate synthase activity
Ontology: molecular_function
Synonyms: L-malate glyoxylate-lyase (CoA-acetylating) activity, acetyl-CoA:glyoxylate C-acetyltransferase (thioester-hydrolysing, carboxymethyl-forming), glyoxylate transacetase activity, glyoxylate transacetylase activity, glyoxylic transacetase activity, malate condensing enzyme activity, malate synthetase activity, malic synthetase activity, malic-condensing enzyme activity
Alternate IDs: None
Definition: Catalysis of the reaction: acetyl-CoA + glyoxylate + H2O = (S)-malate + CoA + H+. Source: RHEA:18181
Comment: Note that this function was formerly EC:4.1.3.2.
History: See term history for GO:0004474 at QuickGO
Chem. react.: has participant glyoxylate; has participant coenzyme A(4-); has participant hydron; has participant water; has participant (S)-malate(2-); has participant acetyl-CoA(4-)
Subset: None
Related: Link to all genes and gene products annotated to malate synthase activity (excluding "regulates").; Link to all direct and indirect annotations to malate synthase activity (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for malate synthase activity (excluding "regulates").

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GO:0003674 molecular_function
GO:0003824 catalytic activity
GO:0016740 transferase activity
GO:0016746 acyltransferase activity
GO:0046912 acyltransferase activity, acyl groups converted into alkyl on transfer
GO:0004474 malate synthase activity

Parents of malate synthase activity (GO:0004474)

subject	relation	object
malate synthase activity	RO:0000057	glyoxylate (CHEBI:36655)
malate synthase activity	RO:0000057	coenzyme A(4-) (CHEBI:57287)
malate synthase activity	RO:0000057	hydron (CHEBI:15378)
malate synthase activity	is_a	acyltransferase activity, acyl groups converted into alkyl on transfer (GO:0046912)
malate synthase activity	RO:0000057	water (CHEBI:15377)
malate synthase activity	RO:0000057	(S)-malate(2-) (CHEBI:15589)
malate synthase activity	RO:0000057	acetyl-CoA(4-) (CHEBI:57288)

This term has no children.

EC: 2.3.3.9
KEGG_REACTION: R00472
MetaCyc: MALSYN-RXN
RHEA: 18181