AmiGO 2: Term Details for "methionyl-tRNA formyltransferase activity" (GO:0004479)

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Term Information

Accession: GO:0004479
Name: methionyl-tRNA formyltransferase activity
Ontology: molecular_function
Synonyms: 10-formyltetrahydrofolate:L-methionyl-tRNA N-formyltransferase activity, N(10)-formyltetrahydrofolic-methionyl-transfer ribonucleic transformylase activity, N-terminal peptidyl-methionine N-formylation, N10-formyltetrahydrofolic-methionyl-transfer ribonucleic transformylase activity, conversion of met-tRNAf to fmet-tRNA, conversion of mitochondrial met-tRNAf to fmet-tRNA, formylmethionyl-transfer ribonucleic synthetase activity, methionyl ribonucleic formyltransferase activity, methionyl-tRNA Met formyltransferase activity, methionyl-tRNA transformylase activity, methionyl-transfer RNA transformylase activity, methionyl-transfer ribonucleate methyltransferase activity, methionyl-transfer ribonucleic transformylase activity, mitochondrial N-terminal peptidyl-methionine N-formylation
Alternate IDs: GO:0070128, GO:0001718
Definition: Catalysis of the reaction: 10-formyltetrahydrofolate + L-methionyl-tRNA + H2O = tetrahydrofolate + N-formylmethionyl-tRNA. Source: EC:2.1.2.9
Comment: None
History: See term history for GO:0004479 at QuickGO
Chem. react.: has participant hydron; has participant (6R)-10-formyltetrahydrofolate(2-); has participant 3'-(N-formyl-L-methionyl)adenylyl(1-) group; has participant 3'-(L-methionyl)adenylyl zwitterionic group; has participant (6S)-5,6,7,8-tetrahydrofolate(2-)
Subset: None
Related: Link to all genes and gene products annotated to methionyl-tRNA formyltransferase activity (excluding "regulates").; Link to all direct and indirect annotations to methionyl-tRNA formyltransferase activity (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for methionyl-tRNA formyltransferase activity (excluding "regulates").

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For more information, please see the ontology relation documentation.

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GO:0071704 organic substance metabolic process
GO:1901360 organic cyclic compound metabolic process
GO:0044238 primary metabolic process
GO:0043170 macromolecule metabolic process
GO:0006139 nucleobase-containing compound metabolic process
GO:0016070 RNA metabolic process
GO:0010467 gene expression
GO:0008152 metabolic process
GO:0034660 ncRNA metabolic process
GO:0090304 nucleic acid metabolic process
GO:0009058 biosynthetic process
GO:0044237 cellular metabolic process
GO:0043412 macromolecule modification
GO:0003674 molecular_function
GO:0141188 nucleic acid catabolic process
GO:0006396 RNA processing
GO:0006399 tRNA metabolic process
GO:0008150 biological_process
GO:0003824 catalytic activity
GO:0044249 cellular biosynthetic process
GO:0009059 macromolecule biosynthetic process
GO:1901576 organic substance biosynthetic process
GO:1901564 organonitrogen compound metabolic process
GO:0009451 RNA modification
GO:0008033 tRNA processing
GO:0140640 catalytic activity, acting on a nucleic acid
GO:0009987 cellular process
GO:1901566 organonitrogen compound biosynthetic process
GO:0019538 protein metabolic process
GO:0016740 transferase activity
GO:0006400 tRNA modification
GO:0140098 catalytic activity, acting on RNA
GO:0019988 charged-tRNA amino acid modification
GO:0016741 transferase activity, transferring one-carbon groups
GO:0006412 translation
GO:0140101 catalytic activity, acting on a tRNA
GO:0071951 conversion of methionyl-tRNA to N-formyl-methionyl-tRNA
GO:0016742 hydroxymethyl-, formyl- and related transferase activity
GO:0006413 translational initiation
GO:0004479 methionyl-tRNA formyltransferase activity

Parents of methionyl-tRNA formyltransferase activity (GO:0004479)

subject	relation	object
methionyl-tRNA formyltransferase activity	BFO:0000050	translational initiation (GO:0006413)
methionyl-tRNA formyltransferase activity	RO:0002162	cellular organisms (NCBITaxon:131567)
methionyl-tRNA formyltransferase activity	is_a	catalytic activity, acting on a tRNA (GO:0140101)
methionyl-tRNA formyltransferase activity	is_a	hydroxymethyl-, formyl- and related transferase activity (GO:0016742)
methionyl-tRNA formyltransferase activity	RO:0000057	hydron (CHEBI:15378)
methionyl-tRNA formyltransferase activity	RO:0000057	(6R)-10-formyltetrahydrofolate(2-) (CHEBI:195366)
methionyl-tRNA formyltransferase activity	RO:0000057	3'-(N-formyl-L-methionyl)adenylyl(1-) group (CHEBI:78844)
methionyl-tRNA formyltransferase activity	RO:0000057	3'-(L-methionyl)adenylyl zwitterionic group (CHEBI:78530)
methionyl-tRNA formyltransferase activity	BFO:0000050	conversion of methionyl-tRNA to N-formyl-methionyl-tRNA (GO:0071951)
methionyl-tRNA formyltransferase activity	RO:0000057	(6S)-5,6,7,8-tetrahydrofolate(2-) (CHEBI:57453)

This term has no children.

EC: 2.1.2.9
MetaCyc: METHIONYL-TRNA-FORMYLTRANSFERASE-RXN
Reactome: R-HSA-5389841
RHEA: 24380