AmiGO 2: Term Details for "dopamine beta-monooxygenase activity" (GO:0004500)

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Term Information

Accession: GO:0004500
Name: dopamine beta-monooxygenase activity
Ontology: molecular_function
Synonyms: dopamine b-hydroxylase activity, (3,4-dihydroxyphenethylamine)beta-mono-oxygenase activity, 3,4-dihydroxyphenethylamine beta-oxidase activity, 3,4-dihydroxyphenethylamine,ascorbate:oxygen oxidoreductase (beta-hydroxylating), 4-(2-aminoethyl)pyrocatechol beta-oxidase activity, MDBH (membrane-associated dopamine beta-monooxygenase), SDBH (soluble dopamine beta-monooxygenase), dopa beta-hydroxylase activity, dopamine beta-hydroxylase activity, dopamine beta-oxidase activity, dopamine hydroxylase activity, dopamine-B-hydroxylase activity, oxygenase, dopamine beta-mono-, phenylamine beta-hydroxylase activity
Alternate IDs: None
Definition: Catalysis of the reaction: L-ascorbate + dopamine + O2 = (R)-noradrenaline + dehydroascorbate + H2O. Source: EC:1.14.17.1, RHEA:19117
Comment: None
History: See term history for GO:0004500 at QuickGO
Chem. react.: has participant L-ascorbate; has participant dopaminium(1+); has participant (R)-noradrenaline(1+); has participant dioxygen; has participant water; has participant monodehydro-L-ascorbate(1-)
Subset: None
Related: Link to all genes and gene products annotated to dopamine beta-monooxygenase activity (excluding "regulates").; Link to all direct and indirect annotations to dopamine beta-monooxygenase activity (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for dopamine beta-monooxygenase activity (excluding "regulates").

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Additional internal viewing options

GO:0003674 molecular_function
GO:0003824 catalytic activity
GO:0016491 oxidoreductase activity
GO:0004497 monooxygenase activity
GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen
GO:0004500 dopamine beta-monooxygenase activity

Parents of dopamine beta-monooxygenase activity (GO:0004500)

subject	relation	object
dopamine beta-monooxygenase activity	RO:0000057	L-ascorbate (CHEBI:38290)
dopamine beta-monooxygenase activity	RO:0000057	dopaminium(1+) (CHEBI:59905)
dopamine beta-monooxygenase activity	RO:0000057	(R)-noradrenaline(1+) (CHEBI:72587)
dopamine beta-monooxygenase activity	RO:0000057	dioxygen (CHEBI:15379)
dopamine beta-monooxygenase activity	is_a	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen (GO:0016715)
dopamine beta-monooxygenase activity	RO:0000057	water (CHEBI:15377)
dopamine beta-monooxygenase activity	RO:0000057	monodehydro-L-ascorbate(1-) (CHEBI:59513)

This term has no children.

EC: 1.14.17.1
KEGG_REACTION: R02535
MetaCyc: DOPAMINE-BETA-MONOOXYGENASE-RXN
Reactome: R-HSA-209891
RHEA: 19117