AmiGO 2: Term Details for "kynurenine 3-monooxygenase activity" (GO:0004502)

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Term Information

Accession: GO:0004502
Name: kynurenine 3-monooxygenase activity
Ontology: molecular_function
Synonyms: kynurenine 3-hydroxylase activity, L-kynurenine,NADPH:oxygen oxidoreductase (3-hydroxylating), L-kynurenine-3-hydroxylase activity, kynurenine hydroxylase activity
Alternate IDs: None
Definition: Catalysis of the reaction: L-kynurenine + H+ + NADPH + O2 = 3-hydroxy-L-kynurenine + H2O + NADP+. Source: EC:1.14.13.9, RHEA:20545
Comment: None
History: See term history for GO:0004502 at QuickGO
Chem. react.: has participant hydron; has participant water; has participant NADPH(4-); has participant L-kynurenine zwitterion; has participant dioxygen; has participant NADP(3-); has participant 3-hydroxy-L-kynurenine zwitterion
Subset: None
Related: Link to all genes and gene products annotated to kynurenine 3-monooxygenase activity (excluding "regulates").; Link to all direct and indirect annotations to kynurenine 3-monooxygenase activity (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for kynurenine 3-monooxygenase activity (excluding "regulates").

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For more information, please see the ontology relation documentation.

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Additional internal viewing options

GO:0003674 molecular_function
GO:0003824 catalytic activity
GO:0016491 oxidoreductase activity
GO:0004497 monooxygenase activity
GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
GO:0004502 kynurenine 3-monooxygenase activity

Parents of kynurenine 3-monooxygenase activity (GO:0004502)

subject	relation	object
kynurenine 3-monooxygenase activity	RO:0000057	hydron (CHEBI:15378)
kynurenine 3-monooxygenase activity	RO:0000057	water (CHEBI:15377)
kynurenine 3-monooxygenase activity	RO:0000057	NADPH(4-) (CHEBI:57783)
kynurenine 3-monooxygenase activity	RO:0000057	L-kynurenine zwitterion (CHEBI:57959)
kynurenine 3-monooxygenase activity	RO:0000057	dioxygen (CHEBI:15379)
kynurenine 3-monooxygenase activity	RO:0000057	NADP(3-) (CHEBI:58349)
kynurenine 3-monooxygenase activity	RO:0000057	3-hydroxy-L-kynurenine zwitterion (CHEBI:58125)
kynurenine 3-monooxygenase activity	is_a	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen (GO:0016709)

This term has no children.

EC: 1.14.13.9
KEGG_REACTION: R01960
MetaCyc: KYNURENINE-3-MONOOXYGENASE-RXN
Reactome: R-HSA-71200
RHEA: 20545