AmiGO 2: Term Details for "steroid 21-monooxygenase activity" (GO:0004509)

Accession: GO:0004509
Name: steroid 21-monooxygenase activity
Ontology: molecular_function
Synonyms: steroid 21-hydroxylase activity, 21-hydroxylase activity, steroid,hydrogen-donor:oxygen oxidoreductase (21-hydroxylating), cytochrome P450 CYP21A1, cytochrome p450 XXIA1 activity
Alternate IDs: None
Definition: Catalysis of the reaction: A C(21) steroid + [reduced NADPH--hemoprotein reductase] + O2 = a 21-hydroxy-C(21)-steroid + [oxidized NADPH--hemoprotein reductase] + H2O. Source: RHEA:65612
Comment: None
History: See term history for GO:0004509 at QuickGO
Chem. react.: has participant 21-hydroxy-C21-steroid; has participant FMN(3-); has participant water; has participant FMNH2(2-); has participant C21-steroid; has participant dioxygen; has participant hydron
Subset: None
Related: Link to all genes and gene products annotated to steroid 21-monooxygenase activity (excluding "regulates").; Link to all direct and indirect annotations to steroid 21-monooxygenase activity (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for steroid 21-monooxygenase activity (excluding "regulates").

Include "regulates"
For more information, please see the ontology relation documentation.

subject	relation	object
steroid 21-monooxygenase activity	RO:0000057	21-hydroxy-C21-steroid (CHEBI:138142)
steroid 21-monooxygenase activity	is_a	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen (GO:0016705)
steroid 21-monooxygenase activity	RO:0000057	FMN(3-) (CHEBI:58210)
steroid 21-monooxygenase activity	RO:0000057	water (CHEBI:15377)
steroid 21-monooxygenase activity	RO:0000057	FMNH2(2-) (CHEBI:57618)
steroid 21-monooxygenase activity	is_a	steroid hydroxylase activity (GO:0008395)
steroid 21-monooxygenase activity	RO:0000057	C21-steroid (CHEBI:61313)
steroid 21-monooxygenase activity	RO:0000057	dioxygen (CHEBI:15379)
steroid 21-monooxygenase activity	RO:0000057	hydron (CHEBI:15378)

subject	relation	object
17-hydroxyprogesterone 21-hydroxylase activity (GO:0103069)	is_a	steroid 21-monooxygenase activity
progesterone 21-hydroxylase activity (GO:0106309)	is_a	steroid 21-monooxygenase activity