Term Information

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Accession
GO:0004512
Name
inositol-3-phosphate synthase activity
Ontology
molecular_function
Synonyms
1L-myo-inositol-1-phosphate lyase (isomerizing), D-glucose 6-phosphate cycloaldolase activity, glucocycloaldolase activity, glucose 6-phosphate cyclase activity, glucose-6-phosphate inositol monophosphate cycloaldolase activity, inositol 1-phosphate synthatase activity, inositol 1-phosphate synthetase activity
Alternate IDs
None
Definition
Catalysis of the reaction: D-glucose 6-phosphate = 1D-myo-inositol 3-phosphate. This reaction requires NAD, which dehydrogenates the CHOH group to CO at C-5 of the glucose 6-phosphate, making C-6 into an active methylene, able to condense with the aldehyde at C-1. Finally, the enzyme-bound NADH reconverts C-5 into the CHOH form. Source: RHEA:10716, EC:5.5.1.4
Comment
None
History
See term history for GO:0004512 at QuickGO
Chem. react.
has participant 1D-myo-inositol 3-phosphate(2-)
has participant D-glucopyranose 6-phosphate(2-)
Subset
None
Include "regulates"
For more information, please see the ontology relation documentation.

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Graph of GO:0004512 from QuickGO

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Parents of inositol-3-phosphate synthase activity (GO:0004512)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
inositol-3-phosphate synthase activity [RO:0000057 relation] RO:0000057  1D-myo-inositol 3-phosphate(2-) (CHEBI:58401)
inositol-3-phosphate synthase activity [RO:0000057 relation] RO:0000057  D-glucopyranose 6-phosphate(2-) (CHEBI:61548)
inositol-3-phosphate synthase activity [is_a relation] is_a  intramolecular lyase activity (GO:0016872)

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