AmiGO 2: Term Details for "DNA endonuclease activity" (GO:0004520)

Term Information

Accession: GO:0004520
Name: DNA endonuclease activity
Ontology: molecular_function
Synonyms: endodeoxyribonuclease activity, DNA nicking activity, endonuclease G activity
Alternate IDs: None
Definition: Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acid by creating internal breaks. Source: ISBN:0198547684, GOC:mah
Comment: None
History: See term history for GO:0004520 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to DNA endonuclease activity (excluding "regulates").; Link to all direct and indirect annotations to DNA endonuclease activity (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for DNA endonuclease activity (excluding "regulates").

Include "regulates"
For more information, please see the ontology relation documentation.

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GO:0008150 biological_process
GO:0008152 metabolic process
GO:0071704 organic substance metabolic process
GO:0003824 catalytic activity
GO:0003674 molecular_function
GO:1901360 organic cyclic compound metabolic process
GO:0044238 primary metabolic process
GO:0016787 hydrolase activity
GO:0043170 macromolecule metabolic process
GO:0006139 nucleobase-containing compound metabolic process
GO:0140640 catalytic activity, acting on a nucleic acid
GO:0016788 hydrolase activity, acting on ester bonds
GO:0090304 nucleic acid metabolic process
GO:0140097 catalytic activity, acting on DNA
GO:0006259 DNA metabolic process
GO:0004518 nuclease activity
GO:0004536 DNA nuclease activity
GO:0004519 endonuclease activity
GO:0004520 DNA endonuclease activity
GO:0016889 DNA endonuclease activity, producing 3'-phosphomonoesters
GO:1990238 double-stranded DNA endonuclease activity
GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters
GO:1905347 endodeoxyribonuclease complex
GO:0009381 excinuclease ABC activity
GO:0048256 flap endonuclease activity
GO:0032078 negative regulation of endodeoxyribonuclease activity
GO:0032079 positive regulation of endodeoxyribonuclease activity
GO:0032071 regulation of endodeoxyribonuclease activity
GO:0015666 restriction endodeoxyribonuclease activity
GO:0044824 retroviral 3' processing activity
GO:0000014 single-stranded DNA endodeoxyribonuclease activity
GO:0016890 site-specific endodeoxyribonuclease activity, specific for altered base
GO:0043765 T/G mismatch-specific endonuclease activity

Parents of DNA endonuclease activity (GO:0004520)

subject	relation	object
DNA endonuclease activity	is_a	endonuclease activity (GO:0004519)
DNA endonuclease activity	is_a	DNA nuclease activity (GO:0004536)

Children of DNA endonuclease activity (GO:0004520)

subject	relation	object
single-stranded DNA endodeoxyribonuclease activity (GO:0000014)	is_a	DNA endonuclease activity
endodeoxyribonuclease activity, producing 5'-phosphomonoesters (GO:0016888)	is_a	DNA endonuclease activity
negative regulation of endodeoxyribonuclease activity (GO:0032078)	RO:0002212	DNA endonuclease activity
retroviral 3' processing activity (GO:0044824)	is_a	DNA endonuclease activity
T/G mismatch-specific endonuclease activity (GO:0043765)	is_a	DNA endonuclease activity
endodeoxyribonuclease activator activity (GO:0140656)	RO:0002629	DNA endonuclease activity
double-stranded DNA endonuclease activity (GO:1990238)	is_a	DNA endonuclease activity
removal of nonhomologous ends (GO:0000735)	BFO:0000051	DNA endonuclease activity
excinuclease ABC activity (GO:0009381)	is_a	DNA endonuclease activity
regulation of endodeoxyribonuclease activity (GO:0032071)	RO:0002211	DNA endonuclease activity
flap endonuclease activity (GO:0048256)	is_a	DNA endonuclease activity
DNA endonuclease activity, producing 3'-phosphomonoesters (GO:0016889)	is_a	DNA endonuclease activity
site-specific endodeoxyribonuclease activity, specific for altered base (GO:0016890)	is_a	DNA endonuclease activity
restriction endodeoxyribonuclease activity (GO:0015666)	is_a	DNA endonuclease activity
endodeoxyribonuclease complex (GO:1905347)	RO:0002215	DNA endonuclease activity
positive regulation of endodeoxyribonuclease activity (GO:0032079)	RO:0002213	DNA endonuclease activity

Reactome: R-HSA-110359; R-HSA-9023941; R-HSA-5690988; R-HSA-5686440; R-HSA-5693608; R-HSA-5687464; R-HSA-5693584; R-HSA-6782224; R-HSA-5686657; R-HSA-6782204