AmiGO 2: Term Details for "glycoprotein endo-alpha-1,2-mannosidase activity" (GO:0004569)

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Term Information

Accession: GO:0004569
Name: glycoprotein endo-alpha-1,2-mannosidase activity
Ontology: molecular_function
Synonyms: endo-alpha-mannosidase activity, endomannosidase activity, glucosyl mannosidase activity, glucosylmannosidase activity, glycoprotein glucosylmannohydrolase activity
Alternate IDs: None
Definition: Catalysis of the hydrolysis of the terminal alpha-glucosyl-(1,3)-mannosyl unit from Glc-Man(9)-(GlcNAc)(2) oligosaccharide component of the glycoprotein produced in the Golgi membrane. Source: EC:3.2.1.130
Comment: None
History: See term history for GO:0004569 at QuickGO
Chem. react.: has participant alpha-D-glucosyl-(1->3)-D-mannopyranose; has participant N(4)-{alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc}-Asn residue; has participant water; has participant N-{alpha-Glc-(1->3)-alpha-Man-(1->2)-alpha-Man-(1->2)-alpha-Man-(1->3)-[alpha-Man-(1->2)-alpha-Man-(1->3)-[alpha-Man-(1->2)-alpha-Man-(1->6)]-alpha-Man-(1->6)]-beta-Man-(1->4)-beta-GlcNAc-(1->4)-beta-GlcNAc}-L-Asn residue
Subset: None
Related: Link to all genes and gene products annotated to glycoprotein endo-alpha-1,2-mannosidase activity (excluding "regulates").; Link to all direct and indirect annotations to glycoprotein endo-alpha-1,2-mannosidase activity (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for glycoprotein endo-alpha-1,2-mannosidase activity (excluding "regulates").

Include "regulates"
For more information, please see the ontology relation documentation.

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OLSVis (interactive)

Additional internal viewing options

GO:0003674 molecular_function
GO:0003824 catalytic activity
GO:0016787 hydrolase activity
GO:0016798 hydrolase activity, acting on glycosyl bonds
GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds
GO:0015923 mannosidase activity
GO:0004559 alpha-mannosidase activity
GO:0004569 glycoprotein endo-alpha-1,2-mannosidase activity

Parents of glycoprotein endo-alpha-1,2-mannosidase activity (GO:0004569)

subject	relation	object
glycoprotein endo-alpha-1,2-mannosidase activity	RO:0000057	alpha-D-glucosyl-(1->3)-D-mannopyranose (CHEBI:52996)
glycoprotein endo-alpha-1,2-mannosidase activity	is_a	alpha-mannosidase activity (GO:0004559)
glycoprotein endo-alpha-1,2-mannosidase activity	RO:0000057	N(4)-{alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc}-Asn residue (CHEBI:60627)
glycoprotein endo-alpha-1,2-mannosidase activity	RO:0000057	water (CHEBI:15377)
glycoprotein endo-alpha-1,2-mannosidase activity	RO:0000057	N-{alpha-Glc-(1->3)-alpha-Man-(1->2)-alpha-Man-(1->2)-alpha-Man-(1->3)-[alpha-Man-(1->2)-alpha-Man-(1->3)-[alpha-Man-(1->2)-alpha-Man-(1->6)]-alpha-Man-(1->6)]-beta-Man-(1->4)-beta-GlcNAc-(1->4)-beta-GlcNAc}-L-Asn residue (CHEBI:59080)

This term has no children.

EC: 3.2.1.130
MetaCyc: 3.2.1.130-RXN
Reactome: R-HSA-964759
RHEA: 54824