Term Information

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Accession
GO:0004588
Name
orotate phosphoribosyltransferase activity
Ontology
molecular_function
Synonyms
OPRT activity, OPRTase activity, orotate phosphoribosyl pyrophosphate transferase activity, orotic acid phosphoribosyltransferase activity, orotidine 5'-monophosphate pyrophosphorylase activity, orotidine monophosphate pyrophosphorylase activity, orotidine phosphoribosyltransferase activity, orotidine-5'-phosphate diphosphorylase activity, orotidine-5'-phosphate pyrophosphorylase activity, orotidine-5'-phosphate:diphosphate phospho-alpha-D-ribosyl-transferase activity, orotidylate phosphoribosyltransferase activity, orotidylate pyrophosphorylase activity, orotidylic acid phosphorylase activity, orotidylic acid pyrophosphorylase activity, orotidylic phosphorylase activity, orotidylic pyrophosphorylase activity
Alternate IDs
None
Definition
Catalysis of the reaction: orotidine 5'-phosphate + diphosphate = orotate + 5-phospho-alpha-D-ribose 1-diphosphate. Source: EC:2.4.2.10
Comment
None
History
See term history for GO:0004588 at QuickGO
Chem. react.
has participant orotidine 5'-phosphate(3-)
has participant diphosphate(3-)
has participant 5-O-phosphonato-alpha-D-ribofuranosyl diphosphate(5-)
has participant orotate
Subset
None
Include "regulates"
For more information, please see the ontology relation documentation.

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Graph of GO:0004588 from QuickGO

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Parents of orotate phosphoribosyltransferase activity (GO:0004588)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
orotate phosphoribosyltransferase activity [RO:0000057 relation] RO:0000057  orotidine 5'-phosphate(3-) (CHEBI:57538)
orotate phosphoribosyltransferase activity [RO:0000057 relation] RO:0000057  diphosphate(3-) (CHEBI:33019)
orotate phosphoribosyltransferase activity [is_a relation] is_a  pentosyltransferase activity (GO:0016763)
orotate phosphoribosyltransferase activity [RO:0000057 relation] RO:0000057  5-O-phosphonato-alpha-D-ribofuranosyl diphosphate(5-) (CHEBI:58017)
orotate phosphoribosyltransferase activity [RO:0000057 relation] RO:0000057  orotate (CHEBI:30839)

This term has no children.

EC
2.4.2.10
MetaCyc
OROPRIBTRANS-RXN
Reactome
R-HSA-73567
RHEA
10380