AmiGO 2: Term Details for "oxoglutarate dehydrogenase (succinyl-transferring) activity" (GO:0004591)

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Term Information

Accession: GO:0004591
Name: oxoglutarate dehydrogenase (succinyl-transferring) activity
Ontology: molecular_function
Synonyms: oxoglutarate dehydrogenase (lipoamide) activity, 2-ketoglutarate dehydrogenase activity, 2-oxoglutarate dehydrogenase activity, 2-oxoglutarate: lipoate oxidoreductase activity, 2-oxoglutarate:dihydrolipoyllysine-residue succinyltransferase-lipoyllysine 2-oxidoreductase (decarboxylating, acceptor-succinylating), 2-oxoglutarate:lipoamide 2-oxidoreductase (decarboxylating and acceptor-succinylating) activity, AKGDH activity, OGDC activity, alpha-ketoglutarate dehydrogenase activity, alpha-ketoglutaric acid dehydrogenase activity, alpha-ketoglutaric dehydrogenase activity, alpha-oxoglutarate dehydrogenase activity, ketoglutaric dehydrogenase activity, oxoglutarate decarboxylase activity, oxoglutarate dehydrogenase activity
Alternate IDs: None
Definition: Catalysis of the reaction: 2-oxoglutarate + lipoamide + H+ = S-succinyldihydrolipoamide + CO2. Source: EC:1.2.4.2
Comment: None
History: See term history for GO:0004591 at QuickGO
Chem. react.: has participant hydron; has participant N(6)-[(R)-lipoyl]-L-lysine residue; has participant N(6)-[(R)-S(8)-succinyldihydrolipoyl]-L-lysine(1-) residue; has participant carbon dioxide; has participant 2-oxoglutarate(2-)
Subset: None
Related: Link to all genes and gene products annotated to oxoglutarate dehydrogenase (succinyl-transferring) activity (excluding "regulates").; Link to all direct and indirect annotations to oxoglutarate dehydrogenase (succinyl-transferring) activity (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for oxoglutarate dehydrogenase (succinyl-transferring) activity (excluding "regulates").

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Additional internal viewing options

GO:0003674 molecular_function
GO:0003824 catalytic activity
GO:0016491 oxidoreductase activity
GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors
GO:0016624 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity

Parents of oxoglutarate dehydrogenase (succinyl-transferring) activity (GO:0004591)

subject	relation	object
oxoglutarate dehydrogenase (succinyl-transferring) activity	is_a	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor (GO:0016624)
oxoglutarate dehydrogenase (succinyl-transferring) activity	RO:0000057	hydron (CHEBI:15378)
oxoglutarate dehydrogenase (succinyl-transferring) activity	RO:0000057	N(6)-[(R)-lipoyl]-L-lysine residue (CHEBI:83099)
oxoglutarate dehydrogenase (succinyl-transferring) activity	RO:0000057	N(6)-[(R)-S(8)-succinyldihydrolipoyl]-L-lysine(1-) residue (CHEBI:83120)
oxoglutarate dehydrogenase (succinyl-transferring) activity	RO:0000057	carbon dioxide (CHEBI:16526)
oxoglutarate dehydrogenase (succinyl-transferring) activity	RO:0000057	2-oxoglutarate(2-) (CHEBI:16810)

This term has no children.

EC: 1.2.4.2
MetaCyc: 2OXOGLUTDECARB-RXN
RHEA: 12188