AmiGO 2: Term Details for "phosphoribosylamine-glycine ligase activity" (GO:0004637)

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Term Information

Accession: GO:0004637
Name: phosphoribosylamine-glycine ligase activity
Ontology: molecular_function
Synonyms: 2-amino-N-ribosylacetamide 5'-phosphate kinosynthase activity, 5'-phosphoribosylglycinamide synthetase activity, 5-phospho-D-ribosylamine:glycine ligase (ADP-forming), GAR, GAR synthetase activity, GARS activity, glycinamide ribonucleotide synthetase activity, glycineamide ribonucleotide synthetase activity, phosphoribosylglycinamide synthetase activity, phosphoribosylglycineamide synthetase activity
Alternate IDs: None
Definition: Catalysis of the reaction: 5-phospho-D-ribosylamine + ATP + glycine = N(1)-(5-phospho-D-ribosyl)glycinamide + ADP + 2 H+ + phosphate. Source: EC:6.3.4.13, RHEA:17453
Comment: None
History: See term history for GO:0004637 at QuickGO
Chem. react.: has participant 5-phospho-beta-D-ribosylaminium(1-); has participant hydron; has participant ADP(3-); has participant N(1)-(5-phospho-beta-D-ribosyl)glycinamide(1-); has participant hydrogenphosphate; has participant ATP(4-); has participant glycine zwitterion
Subset: None
Related: Link to all genes and gene products annotated to phosphoribosylamine-glycine ligase activity (excluding "regulates").; Link to all direct and indirect annotations to phosphoribosylamine-glycine ligase activity (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for phosphoribosylamine-glycine ligase activity (excluding "regulates").

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For more information, please see the ontology relation documentation.

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Additional internal viewing options

GO:0003674 molecular_function
GO:0003824 catalytic activity
GO:0016874 ligase activity
GO:0016879 ligase activity, forming carbon-nitrogen bonds
GO:0004637 phosphoribosylamine-glycine ligase activity

Parents of phosphoribosylamine-glycine ligase activity (GO:0004637)

subject	relation	object
phosphoribosylamine-glycine ligase activity	RO:0000057	5-phospho-beta-D-ribosylaminium(1-) (CHEBI:58681)
phosphoribosylamine-glycine ligase activity	is_a	ligase activity, forming carbon-nitrogen bonds (GO:0016879)
phosphoribosylamine-glycine ligase activity	RO:0000057	hydron (CHEBI:15378)
phosphoribosylamine-glycine ligase activity	RO:0000057	ADP(3-) (CHEBI:456216)
phosphoribosylamine-glycine ligase activity	RO:0000057	N(1)-(5-phospho-beta-D-ribosyl)glycinamide(1-) (CHEBI:143788)
phosphoribosylamine-glycine ligase activity	RO:0000057	hydrogenphosphate (CHEBI:43474)
phosphoribosylamine-glycine ligase activity	RO:0000057	ATP(4-) (CHEBI:30616)
phosphoribosylamine-glycine ligase activity	RO:0000057	glycine zwitterion (CHEBI:57305)

This term has no children.

EC: 6.3.4.13
KEGG_REACTION: R04144
MetaCyc: GLYRIBONUCSYN-RXN
Reactome: R-HSA-73814
RHEA: 17453