AmiGO 2: Term Details for "phosphoribosylaminoimidazolesuccinocarboxamide synthase activity" (GO:0004639)

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Term Information

Accession: GO:0004639
Name: phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
Ontology: molecular_function
Synonyms: 4-((N-succinylamino)carbonyl)-5-aminoimidazole ribonucleotide synthetase activity, 4-(N-succinocarboxamide)-5-aminoimidazole synthetase activity, 4-[(N-succinylamino)carbonyl]-5-aminoimidazole ribonucleotide synthetase activity, 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate:L-aspartate ligase (ADP-forming), 5-aminoimidazole-4-N-succinocarboxamide ribonucleotide synthetase activity, PurC, SAICAR synthase activity, SAICAR synthetase activity, SAICARs activity, phosphoribosylaminoimidazole-succinocarboxamide synthase activity, phosphoribosylaminoimidazole-succinocarboxamide synthetase activity, phosphoribosylaminoimidazolesuccinocarboxamide synthetase activity
Alternate IDs: None
Definition: Catalysis of the reaction: 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate + L-aspartate + ATP = (2S)-2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate + ADP + 2 H+ + phosphate. Source: EC:6.3.2.6, RHEA:22628
Comment: None
History: See term history for GO:0004639 at QuickGO
Chem. react.: has participant ADP(3-); has participant hydron; has participant 5-amino-1-(5-phosphonato-D-ribosyl)imidazolium-4-carboxylate(2-); has participant hydrogenphosphate; has participant SAICAR(4-); has participant L-aspartate(1-); has participant ATP(4-)
Subset: None
Related: Link to all genes and gene products annotated to phosphoribosylaminoimidazolesuccinocarboxamide synthase activity (excluding "regulates").; Link to all direct and indirect annotations to phosphoribosylaminoimidazolesuccinocarboxamide synthase activity (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for phosphoribosylaminoimidazolesuccinocarboxamide synthase activity (excluding "regulates").

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For more information, please see the ontology relation documentation.

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Additional internal viewing options

GO:0003674 molecular_function
GO:0003824 catalytic activity
GO:0016874 ligase activity
GO:0016879 ligase activity, forming carbon-nitrogen bonds
GO:0016881 acid-amino acid ligase activity
GO:0004639 phosphoribosylaminoimidazolesuccinocarboxamide synthase activity

Parents of phosphoribosylaminoimidazolesuccinocarboxamide synthase activity (GO:0004639)

subject	relation	object
phosphoribosylaminoimidazolesuccinocarboxamide synthase activity	RO:0000057	ADP(3-) (CHEBI:456216)
phosphoribosylaminoimidazolesuccinocarboxamide synthase activity	RO:0000057	hydron (CHEBI:15378)
phosphoribosylaminoimidazolesuccinocarboxamide synthase activity	RO:0000057	5-amino-1-(5-phosphonato-D-ribosyl)imidazolium-4-carboxylate(2-) (CHEBI:77657)
phosphoribosylaminoimidazolesuccinocarboxamide synthase activity	RO:0000057	hydrogenphosphate (CHEBI:43474)
phosphoribosylaminoimidazolesuccinocarboxamide synthase activity	RO:0000057	SAICAR(4-) (CHEBI:58443)
phosphoribosylaminoimidazolesuccinocarboxamide synthase activity	RO:0000057	L-aspartate(1-) (CHEBI:29991)
phosphoribosylaminoimidazolesuccinocarboxamide synthase activity	is_a	acid-amino acid ligase activity (GO:0016881)
phosphoribosylaminoimidazolesuccinocarboxamide synthase activity	RO:0000057	ATP(4-) (CHEBI:30616)

This term has no children.

EC: 6.3.2.6
KEGG_REACTION: R04591
MetaCyc: SAICARSYN-RXN
Reactome: R-HSA-73805
RHEA: 22628