AmiGO 2: Term Details for "polypeptide N-acetylgalactosaminyltransferase activity" (GO:0004653)

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Term Information

Accession: GO:0004653
Name: polypeptide N-acetylgalactosaminyltransferase activity
Ontology: molecular_function
Synonyms: UDP-GalNAc:polypeptide N-acetylgalactosaminyl transferase activity, UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase activity, UDP-N-acetyl-D-galactosamine:polypeptide N-acetylgalactosaminyl-transferase activity, UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase activity, UDP-N-acetylgalactosamine-glycoprotein N-acetylgalactosaminyltransferase activity, UDP-N-acetylgalactosamine-protein N-acetylgalactosaminyltransferase activity, UDP-N-acetylgalactosamine:kappa-casein polypeptide N-acetylgalactosaminyltransferase activity, UDP-N-acetylgalactosamine:polypeptide N-acetylgalactosaminyltransferase activity, UDP-N-acetylgalactosamine:protein N-acetylgalactosaminyl transferase activity, UDP-acetylgalactosamine-glycoprotein acetylgalactosaminyltransferase activity, UDP-acetylgalactosamine:peptide-N-galactosaminyltransferase activity, glycoprotein acetylgalactosaminyltransferase activity, polypeptide-N-acetylgalactosamine transferase activity, protein-UDP acetylgalactosaminyltransferase activity, uridine diphosphoacetylgalactosamine-glycoprotein acetylgalactosaminyltransferase activity
Alternate IDs: None
Definition: Catalysis of the reaction: UDP-N-acetyl-D-galactosamine + polypeptide = UDP + N-acetyl-D-galactosaminyl-polypeptide. This reaction is the modification of serine or threonine residues in polypeptide chains by the transfer of a N-acetylgalactose from UDP-N-acetylgalactose to the hydroxyl group of the amino acid; it is the first step in O-glycan biosynthesis. Source: ISBN:0879695595, EC:2.4.1.41
Comment: None
History: See term history for GO:0004653 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to polypeptide N-acetylgalactosaminyltransferase activity (excluding "regulates").; Link to all direct and indirect annotations to polypeptide N-acetylgalactosaminyltransferase activity (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for polypeptide N-acetylgalactosaminyltransferase activity (excluding "regulates").

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For more information, please see the ontology relation documentation.

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GO:0003824 catalytic activity
GO:0016740 transferase activity
GO:0016757 glycosyltransferase activity
GO:0003674 molecular_function
GO:0016758 hexosyltransferase activity
GO:0008194 UDP-glycosyltransferase activity
GO:0008376 acetylgalactosaminyltransferase activity
GO:0140096 catalytic activity, acting on a protein
GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity

Parents of polypeptide N-acetylgalactosaminyltransferase activity (GO:0004653)

subject	relation	object
polypeptide N-acetylgalactosaminyltransferase activity	is_a	acetylgalactosaminyltransferase activity (GO:0008376)
polypeptide N-acetylgalactosaminyltransferase activity	is_a	catalytic activity, acting on a protein (GO:0140096)

This term has no children.

EC: 2.4.1.41
MetaCyc: 2.4.1.41-RXN
Reactome: R-HSA-5096537; R-HSA-9694438; R-HSA-913675; R-HSA-8851619; R-HSA-9683760; R-HSA-5096532