AmiGO 2: Term Details for "porphobilinogen synthase activity" (GO:0004655)

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Term Information

Accession: GO:0004655
Name: porphobilinogen synthase activity
Ontology: molecular_function
Synonyms: aminolevulinate dehydratase activity, delta-aminolevulinic acid dehydratase activity, 5-aminolevulinate hydro-lyase (adding 5-aminolevulinate and cyclizing), 5-aminolevulinate hydro-lyase (adding 5-aminolevulinate and cyclizing; porphobilinogen-forming), 5-levulinic acid dehydratase activity, aminolevulinic dehydratase activity, delta-aminolevulinate dehydratase activity, delta-aminolevulinic acid dehydrase activity, delta-aminolevulinic dehydratase activity
Alternate IDs: None
Definition: Catalysis of the reaction: 2 5-aminolevulinate = 2 H2O + H+ + porphobilinogen. Source: EC:4.2.1.24, RHEA:24064
Comment: None
History: See term history for GO:0004655 at QuickGO
Chem. react.: has participant porphobilinogen(1-); has participant 5-ammoniolevulinate; has participant hydron; has participant water
Subset: None
Related: Link to all genes and gene products annotated to porphobilinogen synthase activity (excluding "regulates").; Link to all direct and indirect annotations to porphobilinogen synthase activity (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for porphobilinogen synthase activity (excluding "regulates").

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GO:0003674 molecular_function
GO:0003824 catalytic activity
GO:0016829 lyase activity
GO:0016835 carbon-oxygen lyase activity
GO:0016836 hydro-lyase activity
GO:0004655 porphobilinogen synthase activity

Parents of porphobilinogen synthase activity (GO:0004655)

subject	relation	object
porphobilinogen synthase activity	RO:0000057	porphobilinogen(1-) (CHEBI:58126)
porphobilinogen synthase activity	RO:0000057	5-ammoniolevulinate (CHEBI:356416)
porphobilinogen synthase activity	RO:0000057	hydron (CHEBI:15378)
porphobilinogen synthase activity	RO:0000057	water (CHEBI:15377)
porphobilinogen synthase activity	is_a	hydro-lyase activity (GO:0016836)

This term has no children.

EC: 4.2.1.24
KEGG_REACTION: R00036
MetaCyc: PORPHOBILSYNTH-RXN
Reactome: R-HSA-189439
RHEA: 24064