AmiGO 2: Term Details for "procollagen-proline 4-dioxygenase activity" (GO:0004656)

Term Information

Accession: GO:0004656
Name: procollagen-proline 4-dioxygenase activity
Ontology: molecular_function
Synonyms: procollagen-proline,2-oxoglutarate-4-dioxygenase activity, collagen proline hydroxylase activity, hydroxylase, collagen proline activity, procollagen-L-proline,2-oxoglutarate:oxygen oxidoreductase (4-hydroxylating) activity, proline protocollagen hydroxylase activity, prolylprotocollagen dioxygenase activity, prolylprotocollagen hydroxylase activity, protocollagen proline 4-hydroxylase activity, protocollagen proline dioxygenase activity, protocollagen proline hydroxylase activity, protocollagen prolyl hydroxylase activity, peptidyl proline hydroxylase activity, proline hydroxylase activity, proline, 2-oxoglutarate dioxygenase activity, proline,2-oxoglutarate 4-dioxygenase activity, prolyl 4-hydroxylase activity, prolyl hydroxylase activity, prolyl-glycyl-peptide, 2-oxoglutarate:oxygen oxidoreductase, 4-hydroxylating activity, protocollagen hydroxylase activity
Alternate IDs: None
Definition: Catalysis of the reaction: procollagen L-proline + 2-oxoglutarate + O2 = procollagen trans-4-hydroxy-L-proline + succinate + CO2. Source: EC:1.14.11.2
Comment: None
History: See term history for GO:0004656 at QuickGO
Chem. react.: has participant trans-4-hydroxy-L-proline residue; has participant carbon dioxide; has participant 2-oxoglutarate(2-); has participant dioxygen; has participant L-proline residue; has participant succinate(2-)
Subset: None
Related: Link to all genes and gene products annotated to procollagen-proline 4-dioxygenase activity (excluding "regulates").; Link to all direct and indirect annotations to procollagen-proline 4-dioxygenase activity (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for procollagen-proline 4-dioxygenase activity (excluding "regulates").

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For more information, please see the ontology relation documentation.

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GO:0003824 catalytic activity
GO:0003674 molecular_function
GO:0016491 oxidoreductase activity
GO:0051213 dioxygenase activity
GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0016706 2-oxoglutarate-dependent dioxygenase activity
GO:0140096 catalytic activity, acting on a protein
GO:0031543 peptidyl-proline dioxygenase activity
GO:0031545 peptidyl-proline 4-dioxygenase activity
GO:0019798 procollagen-proline dioxygenase activity
GO:0004656 procollagen-proline 4-dioxygenase activity
GO:0016222 procollagen-proline 4-dioxygenase complex

Parents of procollagen-proline 4-dioxygenase activity (GO:0004656)

subject	relation	object
procollagen-proline 4-dioxygenase activity	RO:0000057	trans-4-hydroxy-L-proline residue (CHEBI:61965)
procollagen-proline 4-dioxygenase activity	is_a	peptidyl-proline 4-dioxygenase activity (GO:0031545)
procollagen-proline 4-dioxygenase activity	RO:0000057	carbon dioxide (CHEBI:16526)
procollagen-proline 4-dioxygenase activity	RO:0000057	2-oxoglutarate(2-) (CHEBI:16810)
procollagen-proline 4-dioxygenase activity	is_a	procollagen-proline dioxygenase activity (GO:0019798)
procollagen-proline 4-dioxygenase activity	RO:0000057	dioxygen (CHEBI:15379)
procollagen-proline 4-dioxygenase activity	RO:0000057	L-proline residue (CHEBI:50342)
procollagen-proline 4-dioxygenase activity	RO:0000057	succinate(2-) (CHEBI:30031)

Children of procollagen-proline 4-dioxygenase activity (GO:0004656)

subject	relation	object
procollagen-proline 4-dioxygenase complex (GO:0016222)	RO:0002215	procollagen-proline 4-dioxygenase activity

EC: 1.14.11.2
KEGG_REACTION: R03219
MetaCyc: 1.14.11.2-RXN
Reactome: R-HSA-1650808
RHEA: 18945